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左炔诺孕酮宫内节育系统在子宫腺肌病治疗中的价值

Value of Levonorgestrel Intrauterine Contraceptive System in the Treatment of Adenomyosis
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摘要 目的探究左炔诺孕酮宫内节育系统在子宫腺肌病治疗中的价值。方法选取2019年6月至2021年2月平顶山市妇幼保健院收治的92例子宫腺肌病患者为研究对象,按随机数表法分为对照组和观察组,各46例。对照组接受传统治疗,观察组接受左炔诺孕酮宫内节育系统治疗,观察两组患者干预前后血清性激素水平、疼痛、月经血量、焦虑、抑郁以及不良反应发生情况。结果观察组患者干预后黄体生成素(LH)、雌二醇(E_(2))、卵泡刺激素(FSH)等血清性激素水平高于对照组(P<0.05);观察组患者干预后盆腔视觉模拟评分(VAS)、月经血量、焦虑自评量表(SAS)评分及抑郁自评量表(SDS)评分低于对照组(P<0.05);观察组患者经期紊乱、贫血、闭经以及不孕等并发症发生率等低于对照组(P<0.05)。结论对子宫腺肌病患者实施左炔诺孕酮宫内节育器治疗,可改善患者血清性激素水平,降低患者对于疼痛的感知程度,促使经量保证在正常水平范围内,缓解焦虑、抑郁等不良心理状态,减少术后不良反应的发生,提高患者临床治疗效果。 Objective To explore the value of levonorgestrel intrauterine contraceptive system in the treatment of adenomyosis.Methods A total of 92 patients with adenomyosis admitted to the Pingdingshan Maternal and Child Health Hospital from June 2019 to February 2021 were selected as the research objects.According to the random number table method,they were divided into control group and observation group,each with 46 cases.The control group received traditional treatment,and the observation group received levonolestrel intrauterine contraceptive system treatment.The levels of serum sex hormones,pain,menstrual blood volume,anxiety,depression and the incidence of complications before and after the intervention of the two groups were observed.Results The levels of serum sex hormones such as luteinizing hormone(LH),estradiol(E_(2))and follicle stimulating hormone(FSH)in the observation group were higher than those in the control group(P<0.05).The visual analogue score(VAS),menstrual blood volume,self-rating anxiety scale(SAS)and self-rating depression scale(SDS)of the observation group after intervention were lower than those of the control group(P<0.05).The incidence of complications such as menstrual disorder,anemia,amenorrhea and infertility in the observation group was lower than that in the control group(P<0.05).Conclusion The levonorgestrel intrauterine contraceptive system for patients with adenomyosis can effectively improve the serum sex hormone levels,reduce the patients’perception of pain,promote the volume to ensure within the normal level,relieve anxiety,depression and other adverse psychological state,reduce the occurrence of postoperative complications,and improve the clinical treatment effect in patients.
作者 史靖 SHI Jing(Department of Gynecology,Pingdingshan Maternal and Child Health Hospital,Pingdingshan 467002,China)
出处 《河南医学研究》 CAS 2021年第36期6839-6842,共4页 Henan Medical Research
关键词 子宫腺肌病 左炔诺孕酮 宫内节育系统 adenomyosis levonorgestrel intrauterine contraceptive system
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