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GRADE在我国临床实践指南/专家共识中的应用研究 被引量:11

Application of GRADE in Chinese clinical practice guidelines/expert consensus
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摘要 目的了解GRADE在我国临床实践指南/专家共识中的应用情况。方法计算机检索CNKI、WanFang Data、PubMed数据库和医脉通网站,搜集国内外近11年中国大陆学者制订的临床实践指南/专家共识,检索时限均为2010年1月1日~2020年12月31日。由4名研究者独立根据AGREEⅡ工具提取方法学质量条目,按是否使用GRADE分为两组,探究中国临床实践指南/专家共识在方法学质量上的变化和发展情况。结果近年来我国使用GRADE分级系统的临床实践指南/专家共识数量逐年递增,未使用GRADE分级系统的临床实践指南/专家共识方法学质量较低(P<0.01)。结论中国临床实践指南/专家共识对GRADE分级系统的应用仍待提高,应采用GRADE系统来提高临床实践指南/专家共识的方法学质量。 Objective To explore the methodological characteristics of Chinese clinical practice guidelines/expert consensus based on usage of GRADE.Methods CNKI,PubMed,WanFang Data databases,and Medlive.cn were electronically searched to collect Chinese clinical practice guidelines/expert consensus over the past 11 years from January1 st 2010 to December 31 st 2020.Four reviewers independently extracted data according to the content of appraisal of guidelines quality evaluation tool AGREEⅡ.The clinical practice guidelines/expert consensus were divided into two groups based on whether GRADE was used or not.The changes and development of methodological quality in the past 11 years were explored between the two groups.Results In recent years,the number of clinical practice guidelines/expert consensus which used the GRADE in China had increased annually.The practice guidelines/expert consensus which did not use GRADE had lower methodology quality(P<0.01).Conclusions The use of GRADE in clinical practice guidelines/expert consensus requires improvement,and mastering GRADE methodology can effectively improve the methodological quality of the clinical practice guidelines/expert consensus.
作者 黄桥 任相颖 张蓉 李江 闫思宇 王云云 靳英辉 HUANG Qiao;REN Xiangying;ZHANG Rong;LI Jiang;YAN Siyu;WANG Yunyun;JIN Yinghui(Center for Evidence-Based and Translational Medicine,Zhongnan Hospital of Wuhan University,Wuhan 430071,P.R.China;Department of Evidence-Based Medicine and Clinical Epidemiology,The Second Clinical College,Wuhan University,Wuhan 430071,P.R.China;School of Nursing and Health,Henan University,Kaifeng 475000,P.R.China;Department of Neurotumor Disease Diagnosis and Treatment Center,Taihe Hospital,Hubei University of Medicine,Shiyan 442000,P.R.China;School of Health Sciences,Wuhan University,Wuhan 430071,P.R.China;Program Office for Cancer Screening in Urban China,National Cancer Center/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,P.R.China)
出处 《中国循证医学杂志》 CSCD 北大核心 2021年第12期1457-1462,共6页 Chinese Journal of Evidence-based Medicine
基金 国家自然科学基金项目(编号:82174230) 中国医学科学院中央级公益性科研院所基本科研业务费(编号:2020-PT330-001)。
关键词 临床实践指南 专家共识 GRADE 证据等级 推荐意见强度 Clinical practice guideline Expert consensus GRADE Level of evidence Strength of recommendation
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