摘要
目的探讨老年高血压患者轻度认知功能障碍受到合并脑血管血流动力学异常的影响。方法回顾性选取2018年6月至2020年6月本院老年高血压患者60例,依据合并脑血管血流动力学异常情况分为合并组(n=30)、未合并组(n=30)两组,另回顾性选取同期本院老年非高血压人群30例作为对照组,统计分析三组人员的血压、血糖、血脂、CVHI评分、认知功能,二元Logistic回归分析轻度认知功能障碍的影响因素。结果合并组、未合并组、对照组人员的收缩压、舒张压、空腹血糖水平均逐渐降低(P<0.05),CVHI评分逐渐升高(P<0.05),但三组人员的总胆固醇、LDL-C水平比较,差异无统计学意义(P>0.05)。合并组患者的定向力、抽象思维评分均显著低于未合并组、对照组,差异有统计学意义(P<0.05);合并组、未合并组患者的语言、命名、视空间与执行功能、注意与集中、延迟记忆评分均显著低于对照组,差异有统计学意义(P<0.05);合并组、未合并组、对照组人员的MoCA总分逐渐升高(P<0.05)。轻度认知功能障碍的影响因素包括糖尿病、教育年限≤12年、最小流速、CVHI异常、高血压合并CVHI异常(P<0.05)。结论老年高血压患者轻度认知功能障碍受到合并脑血管血流动力学异常的直接影响。
thinking scores of patients in the combined group were significantly lower than those in the uncombined group and the control group,the difference was statistically significant(P<0.05).The language,naming,visual space and executive function,attention and concentration,and delayed memory scores of patients in the combined and uncombined groups were significantly lower than those of the control group,the difference was statistically significant(P<0.05).The total MoCA scores of the combined,uncombined,and control group gradually increased(P<0.05).The influencing factors of mild cognitive dysfunction included diabetes,education years≤12 years,minimum flow rate,abnormal CVHI,and abnormal CVHI combined with hypertension(P<0.05).Conclusion Mild cognitive dysfunction in elderly hypertensive patients is directly affected by abnormal cerebrovascular hemodynamics.
作者
谢玉芳
杨凤
黄小红
刘仕翔
XIE Yufang;YANG Feng;HUANG Xiaohong;LIU Shixiang(Department of Geriatrics,Jiujiang NO.1 People's Hospital in Jiangxi Province,Jiujiang 332000,China)
出处
《中国现代医生》
2021年第32期117-120,共4页
China Modern Doctor
关键词
老年
高血压
轻度认知功能障碍
脑血管血流动力学异常
血压
血糖
血脂
Old age
Hypertension
Mild cognitive impairment
Abnormal cerebrovascular hemodynamics
Blood pressure
Blood glucose
Blood lipids
