摘要
Sweat contains a broad range of critical biomarkers including ions,small molecules,and macromolecules that may indirectly or directly reflect the health status of the human body and thereby help track disease progression.Wearable sweat biosensors enable the collection and analysis of sweat in situ,achieving real-time,continuous,and noninvasive monitoring of human biochemical parameters at the molecular level.This review summarizes the physiological/pathological information of sweat and wearable sweat biosensors.First,the production of sweat pertaining to various electrolytes,metabolites,and proteins is described.Then,the compositions of the wearable sweat biosensors are summarized,and the design of each subsystem is introduced in detail.The latest applications of wearable sweat biosensors for outdoor,hospital,and family monitoring are highlighted.Finally,the review provides a summary and an outlook on the future developments and challenges of wearable sweat biosensors with the aim of advancing the field of wearable sweat monitoring technology.
出处
《Research》
SCIE
EI
CAS
CSCD
2021年第1期631-649,共19页
研究(英文)
基金
supported by the National Key R&D Program of China(2020YFA0709900)
the National Science Fund for Distinguished Young Scholars(21625401)
the National Natural Science Foundation of China(22077101,21701086,21727808)
the Joint Research Funds of Department of Science&Technology of Shaanxi Province and Northwestern Polytechnical University(2020GXLH-Z-008)
the Open Project Program of Wuhan National Laboratory for Optoelectronics(No.2020WNLOKF023)
the ChinaSweden Joint Mobility Project(51811530018)
the Natural Science Basic Research Program of Shaanxi(Program No.2019JLZ-11)
the Fundamental Research Funds for the Central Universities Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX21_1100).