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微粒-TACE同步部分脾栓塞方案用于伴脾功能亢进肝癌患者治疗的近期疗效与安全性分析

Short-term Efficacy and Safety of Micron-TACE Synchronous Partial Splenic Embolization for Hepatocellular Carcinoma Patients with Hypersplenism
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摘要 目的探究微粒-TACE同步部分脾栓塞(PSE)方案,对于伴脾功能亢进肝癌患者的治疗效果。方法选取2020年6月-2021年5月收治的伴脾功能亢进肝癌患者86例,将其均分为两组,分别应用微粒-TACE术治疗以及微粒-TACE术联合PSE治疗,对比两组患者治疗前后肝功能指标变化情况以及不良反应发生率。结果两组患者治疗前肝功能指标差异细微(P>0.05),经治疗后,研究组患者肝功能指标相较于参照组更低,恢复更佳,且治疗过程中不良反应发生率更低,组间差异显著(P<0.05)。结论微粒-TACE同步PSE用于应用于伴脾功能亢进肝癌患者之中,能够取得较为显著的治疗效果,患者肝功能能够得到部分恢复,且不良反应发生率较低,安全性更高。 Objective To explore the therapeutic effect of particle-TACE synchronous partial splenic embolization(PSE) for hepatocellular carcinoma patients with hypersplenism. Methods A total of 86 cases of liver cancer patients with hyplenism admitted to our hospital from June 2020 to May 2021 were selected and divided into two groups, which were treated with microparticle-TACE and microparticle-TACE combined with PSE, respectively. The changes of liver function indexes and the incidence of adverse reactions before and after treatment were compared between the two groups. Results There were slight differences in liver function indexes between the two groups before treatment(P>0.05). After treatment, the liver function indexes of the study group were lower than those of the control group, and the incidence of adverse reactions was lower during treatment, and the difference between the two groups was significant(P<0.05). Conclusions The application of particle-TACE synchronous PSE in patients with liver cancer associated with hypersplenism can achieve significant therapeutic effect, and the liver function of patients can be partially recovered, and the incidence of adverse reactions is low, with higher safety, and it is worthy of clinical promotion and application.
作者 朱席政 徐辉 ZHU Xizheng;XU Hui(Department of Interventional Radiology,Wuhan Subheart General Hospital,Wuhan 430056,China)
机构地区 武汉亚心总医院
出处 《航空航天医学杂志》 2021年第11期1295-1296,共2页 Journal of Aerospace medicine
关键词 微粒-TACE 部分脾栓塞方案 伴脾功能亢进 肝癌 安全性 microparticle-TACE Partial splenic embolization Accompanied by hypersplenism Cancer of the liver security
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