摘要
目的对比分析手术与聚桂醇治疗血管瘤患儿的临床价值。方法方便选取2019年2月—2021年1月间经该院确诊为血管瘤并接受治疗的94例患儿作为研究对象,参照随机动态数字表以两个组别进行划分,每组47例。对照组患儿的治疗方案为常规手术,研究组患儿的治疗方案为硬化剂聚桂醇注射;对比分析两组患儿的临床治疗总有效率、治疗前后的血管内皮细胞指标以及并发症发生率。结果研究组患儿中有9例为治疗有效,37例为治疗显效,治疗总有效率为97.87%,对照组患儿中有14例为治疗有效,25例为治疗显效,治疗总有效率为82.98%,差异有统计学意义(χ^(2)=4.424,P<0.05);治疗前,两组患儿的血管内皮细胞指标差异无统计学意义(P>0.05),治疗后,两组的血管内皮细胞指标与治疗前比较均降低,但组间差异无统计学意义(P>0.05);研究组有1例出现色沉斑,1例出现色减斑,并发症发生率为4.26%,对照组有3例出现色减斑,3例出现溃疡,4例出现色沉斑,2例出现瘢痕,并发症发生率为25.53%,差异有统计学意义(χ^(2)=8.393,P<0.05)。结论针对血管瘤患儿,临床通过硬化剂聚桂醇注射方案进行治疗,相对比手术疗法而言可以取得更为确切的临床效果,且创伤性较小,预后出现并发症的风险性也较低,更易于患儿及其家属接受。
Objective To compare and analyze the clinical value of surgery and cinnamyl alcohol in the treatment of children with hemangioma.Methods Ninety-four children who were diagnosed with hemangioma and received treatment in the hospital from February 2019 to January 2021 were conveniently selected as the research objects.According to the random dynamic number table,they were divided into two groups,with 47 cases in each group.The treatment plan for children in the control group was conventional surgery,and the treatment plan for children in the study group was injection of the sclerosing agent lauryl alcohol;the total effective rate of clinical treatment,vascular endothelial cell indicators before and after treatment,and complications of the two groups were compared and analyzed.Results In the study group,9 cases were effective in treatment,37 cases were effective in treatment,and the total effective rate was 97.87%.in the control group,14 cases were effective in treatment,25 cases were effective in treatment,and the total effective rate was 82.98%,the difference was statistically significant(χ^(2)=4.424,P<0.05);before treatment,there was no significant difference in vascular endothelial cell indexes between the two groups(P>0.05).After treatment,the indicators of vascular endothelial cells of the two groups were reduced compared with those before treatment,but the difference between the groups was not statistically significant(P>0.05);in the study group,1 case had pigmentation and 1 case had pigmentation reduction,the complication rate was 4.26%,and in the control group,there were 3 cases with reduced spots,3 cases with ulcers,4 cases with pigmentation spots,and 2 cases with scars.The complication rate was 25.53%,and the difference was statistically significant(χ^(2)=8.393,P<0.05).Conclusion For children with hemangioma,clinical treatment by the sclerosing agent lauryl alcohol injection can achieve more accurate clinical results than surgical treatment,and is less traumatic,and the risk of prognostic complications is also low,more easily accepted by children and their families.
作者
余志
唐华建
刘国庆
YU Zhi;TANG Huajian;LIU Guoqing(Department of Pediatric Surgery,Foshan Maternal and Child Health Hospital,Foshan,Guangdong Province,528000 China)
出处
《中外医疗》
2021年第34期35-38,共4页
China & Foreign Medical Treatment
基金
佛山市卫生和计生局医学科研课题(20180134)。
关键词
血管瘤
患儿
手术
聚桂醇
血管内皮细胞
并发症
Hemangioma
Children
Surgery
Cinnamyl alcohol
Vascular endothelial cells
Complications
