摘要
芬太尼类物质是实验室合成的强阿片类药物,具有成瘾性高、制备简单和变造衍生容易等特点,流入毒品市场后在全球范围内走私和非法滥用日益严重,且中毒剂量微小,可引起高致死率,对各国的公共健康带来严重威胁。对此,2018年联合国累计规定管制了21种芬太尼类物质,2019年中国政府对芬太尼类物质实行整类管制,以应对化解食用、注射毒品问题带来的风险危害,保障人民身心健康。基于芬太尼类物质的危害,通过对其性质、滥用方式、实验室检测方法及现场快速检测方法等方面展开综述,并对检测技术方法的发展方向进行了简要展望,以期为毒品稽查工作领域研究提供技术参考。
Fentanyl analogues are laboratory-synthesized strong opioids with high addictive properties, simple preparation and easy derivatization. Their introduction to the drug market has shown increasing smuggling and illicit abuse worldwide. In addition, the toxic dose of fentanyl analogues is small, which can cause high mortality and pose a serious threat to public health in various countries. In this regard, 21 fentanyl-related substances were controlled by the United Nations cumulative regulations in 2018, and the Chinese government implemented the whole class control of fentanyl-related substances in 2019 in order to deal with the risk and harm caused by the problem of eating and injecting drugs, and protect people’s physical and mental health. Based on the social harmfulness of fentanyl analogues, we reviewed their properties, abuse method, laboratory detection and on-site rapid detection method. The development of detection technology and method is also briefly prospected in order to provide technical reference for drug inspection research.
作者
孙婧
孙洁芳
郭巧珍
邵兵
SUN Jing;SUN Jiefang;GUO Qiaozhen;SHAO Bing(Beijing Advanced Innovation Center for Food Nutrition and Human Health,College of Veterinary Medicine,China Agricultural University,Beijing 100193,China;Beijing Key Laboratory of Diagnostic and Traceability Technologies for Food Poisoning,Beijing Center for Disease Prevention and Control,Beijing 100013,China;Bejing Research Center for Preventive Medicine,Beijing 100013,China)
出处
《中国食品卫生杂志》
CSCD
北大核心
2021年第6期831-841,共11页
Chinese Journal of Food Hygiene
基金
国家重点研发计划(2018YFC1602700)
国家自然科学基金(U1736201)。
关键词
毒品
芬太尼类物质
检测方法
Drugs
fentanyl analogues
detection methods
