摘要
目的探讨膀胱肿瘤并前列腺增生同期行经尿道等离子电切术对前列腺窝种植转移的影响。方法选取2016年1月至2020年11月间徐州市贾汪区人民医院收治的60例膀胱肿瘤并前列腺增生患者,采用随机数字表法分为观察组和对照组,每组30例。观察组患者同期行经尿道等离子膀胱肿瘤电切术(TURBt)和经尿道等离子前列腺电切术(TUPKP)治疗,对照组患者采用TURBt和TUPKP分期手术治疗,比较两组患者的手术治疗效果、术后并发症、复发情况、前列腺窝种植转移情况及生活质量。结果观察组患者手术治疗总有效率为93.3%,高于对照组的70.0%,差异有统计学意义(P <0.05)。观察组患者术后出现尿道狭窄1例(3.3%),对照组患者出现膀胱颈挛缩2例和尿道口狭窄1例,共3例(10.0%),两组比较,差异无统计学意义(P> 0.05)。术后行6~24个月随访,观察组患者前列腺窝种植转移2例(6.7%),对照组无,两组比较,差异无统计学意义(P>0.05)。术后3~12个月中,观察组患者有2例(6.7%)复发,对照组患者出现10例(33.3%)复发,差异有统计学意义(P <0.05)。治疗后,两组患者生活质量评分均高于治疗前,且观察组患者精神健康、情感职能、活力、生理职能、生理功能和总体健康相关生活质量评分均优于对照组,差异均有统计学意义(均P <0.05)。结论膀胱肿瘤并前列腺增生同期行经尿道等离子电切术手术治疗效果较好,能降低术后膀胱肿瘤复发率,不增加前列腺窝种植转移情况,提高患者术后生活质量,值得临床推广应用。
Objective To investigate the effect of transurethral plasmakinetic resection of bladder tumor and benign prostatic hyperplasia on transcoelomic metastasis of prostate fossa. Methods Sixty patients with bladder tumor and benign prostatic hyperplasia were selected at People’s Hospital of Jiawang District from January 2016 to November 2020. They were randomly divided into an observation group and a control group with 30 patients in each group. The observation group currently underwent transurethral plasmakinetic resection of bladder tumor( TURBt) and transurethral plasma kinetic prostatectomy( TUPKP)and the control group underwent TURBt and TUPKP staging operation. The surgical treatment efficacy,postoperative complications,recurrence,transcoelomic metastasis of prostate fossa and quality of life were compared between the two groups. Results The overall efficacy rate was 93. 3% in the observation group,which was higher than 70. 0% of the control group( P < 0. 05). Urethral stricture occurred in 1 patient in the observation group( 3. 33%) and bladder neck contracture occurred in 2 patients and urethral stricture occurred in 1 patient in the control group( 10. 0%)( P > 0. 05). After follow-up of 6 to 24 months,transcoelomic metastasis of prostate fossa occurred in 2 patients( 6. 7%) in the observation group compared with no patient in the control group( P > 0. 05). At 3 to 12 months after the surgery,recurrence occurred in 2 patients( 6. 7%) in the observation group compared with 10 patients( 33. 3%) in the control group( P <0. 05). The quality of life scores increased after the treatment compared with those before the treatment,and the scores of psychological health,emotional function,vigor,physiological function and general health were better in the observation group than in the control group( all P < 0. 05). Conclusion Transurethral plasmakinetic resection of bladder tumor and benign prostatic hyperplasia simultaneously is effective,which can reduce the postoperative recurrence of bladder cancer and improve quality of life without increasing transcoelomic metastasis of prostate fossa. It is worthy of clinical application and promotion.
作者
吕清东
赵伟
张延春
牛欢庆
王蒙
朱恒
LYU Qing-dong;ZHAO Wei;ZHANG Yan-chun;NIU Huan-qing;WANG Meng;ZHU Heng(Department of Urologic Surgery,People’s Hospital of Jiawang District,Xuzhou 221011,China)
出处
《中国肿瘤临床与康复》
2021年第12期1473-1476,共4页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
膀胱肿瘤
前列腺增生
经尿道等离子电切术
前列腺窝种植转移
Bladder tumors
Benign prostatic hyperplasia
Transurethral plasmakinetic resection
Transcoelomic metastasis of prostate fossa
