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基于动态心电图特征的慢性心力衰竭病人预后预测模型分析 被引量:5

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摘要 目的构建慢性心力衰竭病人基于动态心电图特征的预后预测模型,并验证其效能。方法选取2016年10月—2018年10月于我院就诊的200例慢性心力衰竭病人,病人入院后均采用Holter记录盒记录病人动态心电图,测定并记录病人T波形态恢复(TMR)、血浆N末端脑钠肽前体(NT-proBNP)浓度、左室射血分数(LVEF)、心率震荡和T波电交替情况。病人出院后连续随访1年,观察病人是否发生心源性死亡或心力衰竭恶化等心脏事件,发生心脏事件者纳入研究组(64例),未发生心脏事件者纳入对照组(136例)。结果研究组TMR、NT-proBNP和T波电交替明显高于对照组,震荡斜率(TS)和LVEF明显低于对照组,差异均有统计学意义(P<0.05);但两组震荡初始(TO)比较差异无统计学意义(P>0.05)。多因素Logistic回归分析显示,TMR、TS、NT-proBNP、LVEF和T波电交替均是慢性心力衰竭病人预后的独立危险因素。慢性心力衰竭预后预测的一致性指数为0.932[95%CI(0.843,0.965)]。结论TMR、TS、NT-proBNP、LVEF和T波电交替等危险因素构建的列线图可有效预测慢性心力衰竭病人预后,并具有较好的应用价值。
出处 《中西医结合心脑血管病杂志》 2022年第2期281-284,共4页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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