摘要
目的探讨QRS时限延长、继发性ST-T改变与左束支阻滞患者左室运动功能的相关性。方法选取2020年1—12月该院就诊的左束支阻滞患者80例(观察组),同时选取健康体检者80例作为对照组,均给予十二导联心电图及超声心动图检查。结果观察组左心室射血分数(LVEF)和左心室短轴缩短率(LVFS)分别为(45.56±11.05)%和(22.29±6.11)%,明显低于对照组(P<0.05);观察组QRS时限≥160ms患者LVEF和LVFS分别为(35.84±7.60)%和(16.98±5.57)%,明显低于QRS时限<160 ms患者(P<0.05);观察组有继发性ST-T改变患者LVEF和LVFS分别为(42.06±6.61)%和(19.03±7.03)%,明显低于无继发性ST-T改变患者(P<0.05);观察组左室壁运动减弱患者年龄、QRS时限≥160ms、继发性STT改变比例分别为(56.62±4.16)岁、67.35%和71.43%,明显高于无左室壁运动减弱患者(P<0.05),而LVEF为(44.12±3.65)%,明显低于无左室壁运动减弱患者(P<0.05);Logistic回归分析显示:年龄、QRS时限和继发性ST-T改变是左束支阻滞患者发生左室壁运动减弱的影响因素(OR=1.514、2.809和2.514,P<0.05)。结论 QRS时限延长、继发性ST-T改变与左束支阻滞患者左室收缩功能及室壁运动减弱有关,值得进一步研究。
Objective To investigate the correlation between QRS duration, secondary ST-T changes and left ventricular motor function in patients with left bundle branch block.Methods Eighty patients with left bundle branch block in the First Affiliated Hospital of Army Medical University from January 2020 to December 2020 were selected as the observation group, and 80 healthy people were selected as the control group, were given 12 lead ECG and echocardiography examination.Results The left ventricular ejection fraction(LVEF) and left ventricular short axis shortening rate(LVFS) of the observation group were(45.56±11.05)% and(22.29±6.11)%,which were significantly lower than those of the control group(P<0.05);The LVEF and LVFS of patients with QRS duration≥160 ms in the observation group were(35.84±7.60)% and(16.98±5.57)%,which were significantly lower than those of patients with QRS duration<160 ms(P<0.05);The LVEF and LVFS of patients with secondary ST-T changes in the observation group were(42.06±6.61)% and(19.03±7.03)%,which were significantly lower than those of patients without secondary ST-T changes(P<0.05);The age, QRS duration≥160 ms and the proportion of secondary ST-T changes in patients without left ventricular wall motion weakening of observation group were(56.62±4.16) years, 67.35% and 71.43% respectively, which were significantly higher than those in patients without left ventricular wall motion weakening(P<0.05),while the LVEF was(44.12±3.65)%,which was significantly lower than those in patients without left ventricular wall motion weakening(P<0.05);Logistic regression analysis showed that age, QRS duration and secondary ST-T changes were the influencing factors of left ventricular wall motionweakening in patients with left bundle branch block(OR=1.514,2.809 and 2.514,P<0.05).Conclusion The prolonged QRS duration and secondary ST-T changes are related to the decreased left ventricular systolic function and wall motion in patients with left bundle branch block, is worthy of further study.
作者
向建琴
张超
陈宗涛
XIANG Jianqin;ZHANG Chao;CHEN Zongtao(The First Affiliated Hospital of Army Medical University,Chongqing 400038,China)
出处
《中国煤炭工业医学杂志》
2021年第6期650-654,共5页
Chinese Journal of Coal Industry Medicine
基金
重庆市自然科学基金面上项目(编号:cstc2019jcyj-msxmx0466)。
关键词
QRS时限延长
继发性ST-T改变
左束支阻滞
左室运动功能
Prolonged QRS duration
Secondary ST-T changes
Left bundle branch block
Left ventricular motor function
