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倍他米松磷酸钠致过敏性休克1例报告

A case report of anaphylactic shock caused by betamethasone sodium phosphate
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摘要 报告1例静脉输注注射用倍他米松磷酸钠引起过敏性休克的病例。本研究通过对1例使用倍他米松磷酸钠减轻手术部位水肿,致过敏性休克的住院患者病例进行分析,提示医务人员糖皮质激素在具有抗过敏、抗休克的同时也存在过敏性休克的不良反应。通过文献学习,对过敏反应发生机制、过敏性休克发病机制、首选药物及其抢救措施进行讨论,警戒临床合理使用糖皮质激素类药物,规范技术操作规章程序,密切监测药物不良反应,及时采取正确的抢救措施,避免造成严重后果。 A case of anaphylactic shock caused by intravenous infusion of betamethasone sodium phosphate for injection was reported.A case of an inpatient who used betamethasone sodium phosphate to relieve edema at the surgical site and cause anaphylactic shock was analyzed in this paper.And it was suggested that glucocorticoid has effect of anti-allergy and anti-shock,and it also has adverse reactions of anaphylactic shock.Through literature study,the mechanism of allergic reaction,the pathogenesis of anaphylactic shock,the first choice of drugs and rescue measures were discussed,so as to alert the rational use of glucocorticoid drugs in clinic,standardize technical operation procedures,closely monitor adverse drug reactions,and take correct rescue measures in time to avoid serious consequences.
作者 王宏彦 任丛丛 王庆波 李纪尧 徐晓艳 WANG Hongyan;REN Congcong;WANG Qingbo;LI Jiyao;XU Xiaoyan(Department of Pharmacy,Brain Hospital of Liaocheng People's Hospital,Shandong,Liaocheng 252000,China;Clinical Pharmacy Section,Department of Pharmacy,Liaocheng People's Hospital,Shandong,Liaocheng 252000,China;Department of Neurosurgery,Liaocheng People's Hospital,Shandong,Liaocheng 252000,China)
出处 《中国医药科学》 2021年第24期229-232,236,共5页 China Medicine And Pharmacy
关键词 倍他米松 过敏性休克 糖皮质激素 肾上腺素 过敏 不良反应 Betamethasone Anaphylactic shock Glucocorticoid Adrenaline Allergy Adverse reactions
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