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甲状腺癌及其危险因素 被引量:13

Thyroid carcinoma and associated risk factors
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摘要 甲状腺癌是常见的头颈部肿瘤,其发生与遗传因素和环境因素都有一定关系。目前,甲状腺癌发病率不断增加,但人们对甲状腺癌的发病机制和影响因素尚未完全了解。综合多项临床研究及流行病学调查结果发现,包括放射线暴露、女性激素代谢和肥胖等许多因素可能都与甲状腺癌的发生发展有着重要联系,但还有许多因素如膳食因素与甲状腺癌是否有关尚存争议,因此亟须通过更多的流行病学研究来探索和证实。“甲状腺肿瘤及其危险因素”专栏从女性生殖因素、人群膳食因素包括富碘食物摄入等方面入手,探讨这些因素与甲状腺肿瘤(结节)之间的关系,以期为制订甲状腺癌的预防控制策略提供参考依据。 Thyroid carcinoma is a common cervical tumor.Its occurrence is associated with genetic and environmental factors.The incidence rate of thyroid cancer is increasing.However,the pathogenesis and the influencing factors of thyroid carcinoma are not yet fully understood.Many clinical studies and epidemiological investigations have found that such factors as radiation exposure,female hormone metabolism,and obesity have important links with the occurrence of thyroid cancer,but its association with factors such as dietary factors remains controversial.Therefore,it is urgent to explore and validate the relationship between various factors and thyroid cancer through epidemiological studies.In order to provide reference for the prevention of thyroid cancer,this special column“Thyroid carcinoma and associated risk factors”focused on the associations of female reproductive factors and dietary factors(including intake of iodine-rich foods)with thyroid carcinoma(nodules).
作者 汪正园 臧嘉捷 吴凡 WANG Zhengyuan;ZANG Jiajie;WU Fan(Department􀀁of Nutrition and Health,Division of Health Risk Factors Monitoring and Control,Shanghai Municipal Center for Disease Control and Prevention,Shanghai 200336,China;Shanghai Medical College of Fudan University,Shanghai 200032,China)
出处 《环境与职业医学》 CAS CSCD 北大核心 2021年第11期1169-1172,共4页 Journal of Environmental and Occupational Medicine
基金 上海市加强公共卫生体系建设三年行动计划(2020-2022):重点学科项目(GWV-10.1-XK11),学科带头人项目(GWV-10.2-XD18),优秀青年人才项目(GWV-10.2-YQ22) 上海市卫生健康委员会科研课题(20194Y0443) 达能营养中心膳食营养研究与宣教基金(DIC2019-03) 上海市青年拔尖人才基金(No.2020-8)。
关键词 甲状腺癌 放射 女性生殖 重金属 内分泌干扰物 thyroid carcinoma iodine radiation female reproduction heavy metal endocrine disruptor
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