摘要
目的应用可视化方法分析近20年国内中医药领域原发性肝癌的研究热点及趋势。方法以“中医药”“原发性肝癌”等为研究主题,检索中国知网数据库2000年1月至2020年10月的中文期刊文献,采用CiteSpace软件对纳入文献的作者、机构、关键词进行可视化分析。结果共纳入中文期刊文献2488篇,年发文量呈逐渐上升趋势;发文量最多的作者为凌昌全,形成以凌昌全、方肇勤、陈闯等为核心的团队;研究机构中上海中医药大学发文量最多,不同机构间的合作差异较大;关键词共现网络除去主题词相关的关键词,频次前3位的关键词为“综述”“复方苦参注射液”“介入治疗”,中介中心性前3位的关键词为“细胞凋亡”“小鼠”“复方苦参注射液”,关键词共现网络共形成13个聚类,突现词共出现24个。结论近20年国内中医药领域原发性肝癌的研究内容丰富。目前研究热点趋势为总结临床经验,中医药改善肝癌患者肝功能、免疫功能、癌痛的分子生物学机制。
Objective To analyze the research hotspot and trend of primary liver cancer in the field of Chinese medicine in recent 20 years by using visualization.Methods With“traditional Chinese medicine”and“primary liver cancer”as the research topics,Chinese literatures were searched from CNKI database from January 2000 to October 2020.The authors,institutions and keywords of these literatures were visually analyzed by CiteSpace.Results A total of 2488 Chinese literatures were included,the annual published articles showed a gradually increasing trend.Ling Changquan was the most prolific author,forming teams with Ling Changquan,Fang Zhaoqin and Chen Chuang as the core.Shanghai University of Traditional Chinese Medicine was the most prolific institutions,and the cooperation between different institutions was quite different.Removing subject words relevant keywords,the top three keywords were“review”,“Compound Kushen Injection”and“intervention therapy”,the top three centrality keywords were“apoptosis”,“mouse”and“Compound Kushen Injection”.A total of 13 clusters and 24 emergent words were appeared.Conclusion In recent 20 years,the research content of primary liver cancer in the field of traditional Chinese medicine in China is rich.At present,the hotspots are summarizing clinical experience and the molecular biological mechanism of traditional Chinese medicine improving liver function,immune function and cancer pain in patients with liver cancer.
作者
于惠博
胡佳奇
陈顺泰
陈欣
郑红刚
YU Huibo;HU Jiaqi;CHEN Shuntai;CHEN Xin;ZHENG Honggang(Department of Oncology,Guang’anmen Hospital,China Academy of Chinese Medical Sciences,Beijing100053,China;Graduate School,Beijing University of Chinese Medicine,Beijing100029,China)
出处
《中国医药导报》
CAS
2022年第1期136-140,共5页
China Medical Herald
基金
国家中医药管理局委托办事项目——京津冀名老中医药专家朴炳奎学术传承推广项目(GZY-GCS-2018-071)。
