摘要
目的:比较单独使用激素类药物和单独使用半导体激光与联合应用两者治疗牙龈扁平苔藓的临床疗效。方法:收集2017年6月~2019年6月牙龈扁平苔藓患者116例,根据其治疗方法分为三组,分别予曲安奈德口腔软膏涂抹于病损处(软膏组)、半导体激光局部照射(激光组)、先用半导体激光局部照射再用曲安奈德口腔软膏涂抹于病损处(联合组)。比较治疗前、治疗后1周、2周、1个月三组患者的病损面积、疼痛程度评分及症状体征评分。结果:治疗前,三组病损面积、疼痛程度评分及症状体征评分差异无统计学意义(P>0.05);治疗后,三组病损面积均缩小(P<0.05),疼痛程度评分及症状体征评分均降低(P<0.05),治疗后1周、2周和1个月,联合组病损面积均小于软膏组和激光组,疼痛程度评分及症状体征评分均低于软膏组和激光组,差异均有统计学意义(P<0.05)。结论:曲安奈德口腔软膏与半导体激光联合治疗牙龈扁平苔藓效果优于单独使用激素类药物和单独使用激光,可最大限度减轻患者症状,缓解疼痛,促进创面愈合。
Objective To compare the clinical efficacy of steroid drugs alone and semiconductor laser alone and combined with semiconductor laser in the treatment of gingival lichen planus(GLP).Method 116 patients with gingival lichen planus treated in our hospital from June 2017 to June 2019 were collected and divided into three groups according to their treatment methods.Triamcinolone acetonide oral ointment was applied to the lesion(Ointment group)and semiconductor laser local irradiation was applied to the lesion(Laser group).First,local irradiation of semiconductor laser and then triamcinolone acetonide oral ointment was applied to the lesion(Combined).The lesion area,pain score and symptom and sign score were compared among the three groups before treatment,1 week,2 weeks and 1 month after treatment.Results Before treatment,there was no significant difference in lesion area,pain degree and symptom and sign scores among the three groups(P>0.05).After treatment,the lesion area of the three groups decreased(P<0.05),and the scores of pain degree and symptoms and signs decreased(P<0.05).At 1 week,2 weeks and 1 month after treatment,the lesion area of the combined group was smaller than that of the ointment group and laser group.the scores of pain degree and symptoms and signs were lower than those in ointment group and laser group,and the differences were statistically significant(P<0.05).Conclusion The effect of triamcinolone acetonide oral ointment combined with semiconductor laser in the treatment of gingival lichen planus is better than that of hormone drugs and laser alone,which can minimize symptoms,relieve pain and promote wound healing.
作者
齐海涛
曹山松
聂廷洪
QI Hai-tao;CAO Shan-song;NIE Yan-hong(Department of Stomatology,The people′s Hospital of Tianjin Baodi District,Tianjin 301800,China)
出处
《吉林医学》
CAS
2022年第1期153-156,共4页
Jilin Medical Journal
关键词
曲安奈德口腔软膏
半导体激光
牙龈扁平苔藓
Triamcinolone acetonide oral ointment
Semiconductor laser
Gingival lichen planus
