摘要
随着光热纳米材料的开发,基于近红外光激发的光热疗法在细菌感染的伤口治疗中显示出巨大的潜力。同时,为提高伤口感染部位的光热抗菌效果,降低光热对健康组织的高温损伤,靶向细菌策略也逐渐被应用于伤口的光热治疗中。本文分类介绍了常用的光热纳米材料及其靶向细菌策略,阐述了它们在光热抗菌治疗,尤其是在细菌感染伤口中的应用,分析了靶向光热抗菌疗法在伤口愈合应用中面临的难题与挑战,最后对靶向光热抗菌材料的发展提出展望,以期为伤口光热治疗提供一条新的思路。
With the development of photothermal nanomaterials,photothermal therapy based on near-infrared light excitation shows great potential for the bacterial infected wound treatment.At the same time,in order to improve the photothermal antibacterial effect of wound infection and reduce the damage of high temperature and heat to healthy tissue,the targeted bacteria strategy has been gradually applied in wound photothermal therapy.In this paper,several commonly used photothermal nanomaterials as well as their targeted bacterial strategies were introduced,and then their applications in photothermal antibacterial therapy,especially in bacterial infected wounds were described.Besides,the challenges of targeted photothermal antibacterial therapy in the wound healing application were analyzed,and the development of photothermal materials with targeted antibacterial property has prospected in order to provide a new idea for wound photothermal therapy.
作者
袁香楠
谭绍洁
高晶(综述)
王璐(审校)
YUAN Xiangnan;TAN Shaojie;GAO Jing;WANG Lu(Key Laboratory of Biomedical Textile Materials and Technology in Textile Industry,Donghua University,Shanghai 201620,P.R.China;College of Textiles,Donghua University,Shanghai 201620,P.R.China)
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2022年第1期207-216,共10页
Journal of Biomedical Engineering
关键词
细菌感染
光热纳米材料
靶向细菌
光热抗菌
伤口愈合
Bacterial infection
Photothermal nanomaterials
Targeted bacteria
Photothermal antibacterial properties
Wound healing
