摘要
目的:探究快速自凝双丙烯酸树脂(SWIFT-TEMP)暂时冠在口腔修复中的应用及其对龈沟液炎症因子、基质金属蛋白酶-8(MMP-8)表达水平的影响。方法:根据暂时冠修复方式不同将152例口腔修复患者分为对照组和观察组,对照组70例患者(126个牙单位)采用自凝塑料制作暂时冠,观察组82例(147个牙单位)采用SWIFT-TEMP材料制作暂时冠;比较两组患者暂时冠的修复效果、牙龈健康情况、患者对戴暂时冠后的满意情况及龈沟液的炎症因子、MMP-8、天门冬氨酸氨基转移(AST)、碱性磷酸酶(ALP)及内毒素水平变化。结果:戴暂时冠两周后,观察组表面、解剖形态、边缘完整性的评价、牙龈健康程度、食物嵌塞、形态、颜色、异味情况调查结果均优于对照组,差异有统计学意义(P<0.05);戴暂时冠两周后,两组患者龈沟液的TNF-α、IL-6、MMP-8、ALP、AST、内毒素水平均高于备牙前(P<0.05),但观察组均低于对照组(P<0.05)。结论:SWIFT-TEMP暂时冠的修复效果好于自凝塑料,牙龈健康程度高,患者更满意,对龈沟液炎性因子及MMP-8影响更小。
Objective:To explore the application of fast self-solidifying double acrylate resin(SWIFT-TEMP)temporary crown in oral repair and its influences on expressions of inflammatory factors and matrix metalloproteinase-8(MMP-8)in gingival crevicular fluid(GCF).Methods:According to different repair methods of temporary crown,152 patients were divided into control group(70 cases,126 dental units,temporary crown made with self-solidifying plastics)and observation group 82 cases,147 dental units,temporary crown made with SWIFT-TEMP materials.The repair effect of temporary crown,gingival health,satisfaction with temporary crowns,changes of inflammatory factors in GCF,MMP-8,aspartate transaminase(AST),alkaline phosphatase(ALP)and endotoxin were compared between the two groups.Results:After 2 week of temporary crown wearing,evaluation on surface,anatomical morphology and edge integrity,gingival health and the investigation results(food impaction,morphology,color,unpleasant odor)in observation group were better than those in control group(P<0.05).After 2 week of temporary crown wearing,levels of TNF-α,IL-6 and MMP-8 in GCF,ALP,AST and endotoxin were higher than those before tooth preparation in both groups,which were lower in observation group than those in control group(P<0.05).Conclusion:The repair effect of SWIFT-TEMP temporary crown is better than that of self-solidifying plastics,with higher gingival health and patients satisfaction,and fewer effects on inflammatory factors and MMP-8 in GCF.
作者
曲云鹏
胡雪婷
王雪峰
QU Yun-peng;HU Xue-ting;WANG Xue-feng(Department of Stomatology,Liaoyang Central Hospital,Liaoyang 111000,Liaoning,China)
出处
《川北医学院学报》
CAS
2022年第2期228-231,235,共5页
Journal of North Sichuan Medical College
关键词
口腔修复
牙体及牙列缺损
暂时冠
快速自凝双丙烯酸树脂
龈沟液
炎症因子
基质金属蛋白酶-8
Oral repair
Tooth body and dentition defect
Temporary crown
Fast self-solidifying double acrylate resin
Gingival crevicular fluid
Inflammatory factor
Matrix metalloproteinase-8
