摘要
目的探讨常规西药联合健脾调肝法治疗2型糖尿病胃肠功能紊乱患者的临床价值。方法选取2019年3月至2021年1月盘锦市人民医院收治的102例2型糖尿病胃肠功能紊乱患者作为研究对象,按随机数字表法分为对照组与观察组,各51例。对照组患者单纯接受常规西药治疗,观察组患者在对照组基础上接受健脾调肝法(应用以葛根、党参、茯苓、炒白术、当归、鸡内金等中药组成的健脾理气疏肝方)治疗,比较两组治疗有效率、空腹血糖(FBG)、餐后2h血糖(2h PBG)以及糖化血红蛋白(Hb A1c)、胃排空率、肠鸣音。结果观察组治疗有效率高于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者FBG、2h PBG、Hb A1c水平低于对照组,差异有统计学意义(P<0.05);治疗后,观察组胃排空率、肠鸣音高于对照组,差异有统计学意义(P<0.05)。结论健脾调肝法治疗2型糖尿病胃肠功能紊乱疗效显著,应用价值较高。
Objective To explore the therapeutic effect of conventional Western medicine combined with the method of strengthening the spleen and regulating the liver in the treatment of gastrointestinal dysfunction in type 2 diabetes. Methods A total of 102 patients with type 2 diabetes gastrointestinal dysfunction admitted to Panjin City People’s Hospital from March 2019 to January 2021 as the research objects, and were divided them into a control group and an observation group by random number table method. Patients in the control group received conventional Western medicine treatment, and patients in the observation group received the spleen-regulating liver-regulating method on the basis of the control group(applying the spleen, qi, and liver-regulating Formula composed of Radix Puerariae, Radix Codonopsis, Poria, Fried Rhizoma Atractylodis Macrocephalae,Radix Angelicae Sinensis, Endothelium Corneum Gigeriae Galli, etc.) Treatment effectiveness, fasting blood glucose(FBG), 2 h postprandial blood glucose(2 hPBG) and glycosylated hemoglobin(HbA1 c), gastric emptying rate, bowel sounds were compared between the 2 groups.Results The total effective rate of treatment in the observation group was higher than that in the control group, and the difference was statistically significant(P<0.05);after treatment, the observation group patients’ FBG and 2 h PBG, HbA1 c were lower than those in the control group, and the difference was statistically significant(P<0.05). After treatment, the gastric emptying rate and bowel sounds of the observation group were higher than those of the control group, the difference was statistically significant(P<0.05). Conclusion The method of invigorating the spleen and regulating the liver has a significant effect on the treatment of gastrointestinal dysfunction of type 2 diabetes, and its application value is relatively high.
作者
姜思羽
姜飞飞
JIANG Si-Yu;JIANG Fei-Fei(Internal First Department Ward,Panjin City People's Hospital,Panjin 124221,China)
出处
《中国药物经济学》
2022年第1期110-113,共4页
China Journal of Pharmaceutical Economics
关键词
2型糖尿病
胃肠功能紊乱
健脾调肝法
枸橼酸莫沙必利片
疗效
Type 2 diabetes
Gastrointestinal dysfunction
Invigorating the spleen and regulating liver
Mosapride citrate tablets
Curative effect
