摘要
目的探讨极量间苯三酚在宫颈条件欠佳的胎膜早破产妇产程中的应用效果。方法选取2020年1月至2021年1月就诊于大连市妇女儿童医疗中心(集团)的要求自然分娩、宫颈Bishop评分<6分的120例胎膜早破产妇作为研究对象,按照产妇来院的先后顺序,由住院处分配至产一病房及其他产科病房,其中产一病房的60例产妇为观察组,给予间苯三酚共200 mg+地西泮10 mg;其他产科病房的60例产妇为对照组,仅给予地西泮10 mg。常规观察产程进展,比较两组患者的宫颈扩张速度、产程时间、阴道分娩率、中转剖宫产率、产后出血量、宫内感染率及新生儿Apgar评分。结果观察组的宫颈扩张速度、阴道分娩率高于对照组,差异有统计学意义(P<0.05);观察组的中转剖宫产率、宫内感染率均低于对照组,差异有统计学意义(P<0.05);观察组的第一产程潜伏期、活跃期时间均短于对照组,差异有统计学意义(P<0.05);观察组的产后2 h出血量少于对照组,差异有统计学意义(P<0.05);两组的第二产程时间及新生儿Apgar评分比较,差异无统计学意义(P>0.05)。结论极量间苯三酚联合地西泮能够使宫口扩张速度加快,第一产程的潜伏期和活跃期时间缩短,提高了阴道分娩率,降低了中转剖宫产率及产后出血量,且对于新生儿结局无明显影响。
Objective To explore the application effect of maximum Phloroglucinol in the labor process of premature rupture of membranes with poor cervical conditions.Methods From January 2020 to January 2021,120 pregnant women with premature rupture of membranes admitted to Dalian Women and Children′s Medical Center(Group)who required natural childbirth and cervical Bishop score less than 6 scores were selected as the research objects.According to the sequence of their coming to the hospital,they were assignned to the first maternity ward and other obstetric wards.Among them,60 parturients in the first maternity ward were in the observation group,and they were given Phloroglucinol 200 mg^(^(+))Diazepam 10 mg.The rest of 60 pregnant women in other obstetric wards were selected as the control group and were only given Diazepam 10 mg.The progress of labor process was observed routinely.The cervical dilatation rate,labor process time,vaginal delivery rate,conversion to cesarean section rate,postpartum hemorrhage,intrauterine infection rate and neonatal Apgar score were compared between the two groups.Results The cervical dilatation rate and vaginal delivery rate in the observation group were higher than those in the control group,the differences were statistically significant(P<0.05).The rate of conversion to cesarean section and intrauterine infection in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).The latency and active period of the first stage of labor in the observation group were shorter than those in the control group,the differences were statistically significant(P<0.05).The amount of postpartum hemorrhage at 2 hours after delivery in the observation group was less than that in the control group,the difference was statistically significant(P<0.05).There was no significant difference in the second stage of labor and neonatal Apgar score between the two groups(P>0.05).Conclusion Maximum Phloroglucinol combined with Diazepam can accelerate the expansion of uterine orifice,shorten the latency and active period of the first stage of labor process,improve the vaginal delivery rate,reduce the conversion rate of cesarean section and the amount of postpartum hemorrhage,and have no significant effect on the outcome of newborns.
作者
由明学
李颖
杨永华
YOU Mingxue;LI Ying;YANG Yonghua(The First Delivery Ward,Dalian Women and Children′s Medical Center(Group),Liaoning Province,Dalian 116011,China)
出处
《中国当代医药》
CAS
2022年第5期105-107,111,共4页
China Modern Medicine
关键词
间苯三酚
产程
产后出血
胎膜早破
Phloroglucinol
Labor process
Postpartum hemorrhage
Premature rupture of membranes
