摘要
研制了一种基于聚合物平板波导-金纳米颗粒(AuNPs)的表面增强拉曼散射(SERS)基底,长程检测了罗丹明6G(R6G)的SERS信号,对基底的增强性能和重复性进行了分析。实验结果表明:SERS信号强度随着探测距离的增加先增大后减小,在探测距离为10 mm时SERS信号达到最大值;该基底对R6G的检测限为10^(-7)mol/L,增强因子为4.3×10^(4);R6G各特征峰强度的相对标准偏差(RSD)在3%左右,具有较好的重复性。该聚合物平板波导-AuNPs SERS基底能够有效长程检测SERS信号,为生物样本分子的无损检测奠定了基础。
A surface-enhanced Raman scattering(SERS) substrate based on polymeric flat-plate waveguide and gold nanoparticles(AuNPs) is developed.The SERS signal of rhodamine 6 G(R6 G) is detected in the long range,and the enhancement performance and reproducibility of the substrate are analyzed.The experimental results show that the SERS signal increases and then decreases with increasing detection distance,reaching a maximum at a detection distance of 10 mm;the detection limit of the substrate for R6 G is 10^(-7) mol/L and the enhancement factor is 4.3×10^(4);the relative standard deviation(RSD) of each characteristic peak intensity of R6 G is around 3% and has good repeatability.The polymeric flat-plate waveguide-AuNPs substrate can effectively detect SERS signals in a long range,laying the foundation for the non-destructive detection of molecules in biological samples.
作者
刘少平
姜小明
赖林
刘家瑜
钟征源
薄晓晗
许茜
Liu Shaoping;Jiang Xiaoming;Lai Lin;Liu Jiayu;Zhong Zhengyuan;Bo Xiaohan;Xu Qian(College of Optoelectronic Engineering,Chongqing University of Posts and Telecommunications,Chongqing 400065,China;College of Bioinformatics,Chongqing University of Posts and Telecommunications,Chongqing 400065,China)
出处
《激光与光电子学进展》
CSCD
北大核心
2021年第23期379-385,共7页
Laser & Optoelectronics Progress
基金
国家自然科学基金(61801069)。
关键词
光谱学
表面增强拉曼散射
平板波导
长程检测
聚合物
spectroscopy
surface-enhanced Raman scattering
flat-plate waveguide
long range detection
polymeric
