摘要
目的研究新型冠状病毒肺炎(COVID-19)患者舌象分布、色度、纹理变化与中医分期、证候的关系。方法采集来自武汉地区临床一线的920例新型冠状病毒肺炎患者的舌象临床资料,对各证候患者的舌象特征、Lab的色彩模式下的参数及影像组学参数进行统计分析。结果新型冠状病毒肺炎初期患者舌象以淡红舌(76.00%)、薄苔(76.00%)、白苔(86.00%)、腻苔(92.00%)为主;中期患者多见红舌(25.75%)或淡红舌(22.31%)、瘀斑瘀点舌(21.86%),苔色白苔(51.80%)、黄白相兼苔(28.29%)、黄苔(18.71%)均可见,苔质以腻苔为主(94.91%);危重期多见绛舌(57.14%)或红舌(14.29%),舌苔多厚(54.76%)、腻(52.38%)、腐(28.57%),或可见剥脱(16.28%)或无苔(9.52%);恢复期患者以淡红舌(45.00%)、白苔(83.13%)、薄苔(79.38%)为主,舌质多见齿痕舌(43.75%)、裂纹舌(38.13%),还可见剥脱苔(22.50%)。Lab模式中的舌、苔数值与检测到的12个影像组学参数均值均与中医分期或证候具有相关性改变,差异均有统计学意义(P<0.05)。结论新型冠状病毒肺炎患者的舌象特点与中医分期、证候具有一定的相关性,研究从量化的角度客观分析了新型冠状病毒肺炎舌象的色度、纹理改变,对新型冠状病毒肺炎临床辨证提供标准化参考,也为舌象诊断的标准化发展提供客观依据。
Objective To study the relationship between the distribution,chroma and texture changes of tongue manifestations in patients with the novel coronavirus pneumonia and TCM staging and syndromes.Methods The clinical data of tongue manifestations of 920 patients with the novel coronavirus pneumonia in Wuhan were collected,and their tongue manifestation features,Lab color mode parameters and radiomics parameters were statistically analyzed.Results The tongue manifestations of the patients with the novel coronavirus pneumonia in the early stage were mainly characterized by light red tongue (76.00%),thin fur (76.00%),white fur (86.00%) and greasy fur (92.00%).While in the middle stage,they were mainly characterized by red tongue (25.75%) or light red tongue (22.31%),ecchymosis tongue (21.86%),by white fur (51.80%),yellow and white fur (28.29%),yellow fur (18.71%) in color,and mainly by greasy fur (94.91%) in tongue character.In the critical stage,the most common tongue types were deep red tongue (57.14%) or red tongue (14.29%),thick tongue fur (54.76%),greasy fur (52.38%),curdy fur (28.57%),putrid tongue fur (16.28%) or no coating (9.52%).The patients in the convalescent stage mainly had light red tongue (45.00%),white fur (83.13%),thin fur (79.38%),teeth-printed tongue (43.75%),fissured tongue (38.13%),and putrid tongue fur (22.50%).The tongue and fur values in the Lab mode and the detected mean values of 12 radiomics parameters were correlated with TCM stages or syndromes,and the differences were statistically significant (P<0.05).Conclusion The tongue manifestation features of the patients with the novel coronary pneumonia are correlated with TCM staging and syndromes.The study objectively analyzes the chroma and texture changes of the tongue manifestations of those novel coronary pneumonia patients from a quantitative point of view,provides a standardized reference for clinical syndrome differentiation of the disease and an objective basis for the standardized development of tongue manifestation diagnosis as well.
作者
陈锐
孙阿茹
陈娟
朱蔚
颜仕星
聂维辰
仝小林
CHEN Rui;SUN Aru;CHEN Juan;ZHU Wei;YAN Shixing;NIE Weichen;TONG Xiaolin(Changchun University of Chinese Medicine,Changchun 130117,China;Xiangyang Hospital of Integrated Traditional Chinese and Western Medicine,Xiangyang 441004,China;The 942nd Hospital of the PLA Joint Logistic Support Force,Yinchuan 750003,China;Shanghai Daosheng Medical Technology Co.,LTD.,Shanghai 201203,China;Beijing University of Chinese Medicine,Beijing 100029,China;Guang’anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)
出处
《长春中医药大学学报》
2022年第3期295-300,共6页
Journal of Changchun University of Chinese Medicine
基金
吉林省中医药管理局(吉林省中医药标准化项目)(zybz-2020-005)。
关键词
新型冠状病毒肺炎
舌象
中医证候
相关性研究
novel coronavirus pneumonia
tongue manifestation
TCM syndrome
correlation study
