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乳头瘤病毒检查在早期宫颈癌筛查中的应用分析 被引量:3

Application analysis of papillomavirus detection in early cervical cancer screening
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摘要 目的观察乳头瘤病毒检查在早期宫颈癌筛查中的应用价值。方法选取妇科体检中行早期宫颈癌筛查的1268例女性,根据检查方法不同分为A组(531例)、B组(443例)、C组(128例)、D组(166例)。A组采用宫颈刮片检查,B组采用液基薄层细胞检查,C组采用乳头瘤病毒+宫颈刮片检查,D组采用乳头瘤病毒+液基薄层细胞检查。对比四组阳性检出率。结果A组阳性检出9例,阳性检出率为1.69%;B组检出阳性8例,阳性检出率为1.81%;C组检出阳性25例,阳性检出率为19.53%;D组检出阳性34例,阳性检出率为20.48%。C组、D组检出阳性率均高于A组、B组,差异均有统计学意义(P<0.05);而A组与B组、C组与D组的阳性检出率对比,差异均无统计学意义(P>0.05)。结论在妇科体检中,早期宫颈癌筛查对尽早发现宫颈癌意义重大,乳头瘤病毒联合宫颈刮片检查或乳头瘤病毒联合液基薄层细胞检查的阳性检出率均比较高,在临床中有推广应用价值。 Objective To observe the application value of papillomavirus detection in early cervical cancer screening.Methods A total of 1268 women who underwent early cervical cancer screening in gynecological physical examination were selected and divided into group A(531 cases),group B(443 cases),group C(128 cases),and group D(166 cases)according to different examination methods.Group A used cervical smear examination,group B used liquid-based thin-layer cytology,group C used papillomavirus+cervical smear examination,and group D used papillomavirus+liquid-based thin-layer cytology.The positive detection rates of the four groups were compared.Results In group A,9 positive cases were detected,with a positive detection rate of 1.69%;in group B,8 positive cases were detected,with a positive detection rate of 1.81%;in group C,25 positive cases were detected,with a positive detection rate of 19.53%;in group D,34 positive cases were detected,with a positive detection rate of 20.48%.The positive detection rates of group C and group D were higher than those of group A and group B,and the differences were statistically significant(P<0.05).There was no statistically significant difference in the positive detection rates between group A and group B,group C and group D(P>0.05).Conclusion In gynecological physical examination,early cervical cancer screening is of great significance for the early detection of cervical cancer.In terms of inspection methods,the positive detection rate of papillomavirus combined with cervical smear or papillomavirus combined with liquid-based thin-layer cytology is relatively high,and has the value of promotion and application in clinical practice.
作者 李正岩 LI Zheng-yan(Women’s Health Section,Maternal and Child Health Care of Pulandian District,Dalian 116200,China)
出处 《中国现代药物应用》 2022年第4期105-108,共4页 Chinese Journal of Modern Drug Application
关键词 妇科体检 宫颈癌 早期筛查 阳性检出率 Gynecological physical examination Cervical cancer Early screening Positive detection rate
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