摘要
目的分析研究盐酸右美托咪定应用在缺血性脑卒中介入治疗麻醉中的临床效果。方法方便选取2019年9月—2020年9月收治的120例缺血性脑卒中患者,随机均分为两组,分别为研究组和参比组,研究组运用常规全麻方法,并应用盐酸右美托咪定,而参比组仅应用常规全麻方法,针对两组临床效果展开比较分析。结果研究组急性生理与慢性健康评分(APACHEⅡ)评分(8.41±1.08)分低于参比组,Steward苏醒评分(5.72±0.14)分、格拉斯哥昏迷评分(GCS)评分(14.18±0.63)分均高于参比组,差异有统计学意义(t=19.536、34.637、30.604,P<0.05);手术开始及结束时的心率水平(84.25±7.16)、(82.32±6.28)次/min、手术开始及结束时的血压水平(92.24±3.58)、(90.17±5.24)mmHg均低于参比组,差异有统计学意义(t=9.540、4.078、15.562、4.852,P<0.05);麻醉恢复时间(7.71±1.84)min、手术时长(72.58±10.43)min、拔管时间(12.11±1.58)min均短于参比组,差异有统计学意义(t=17.531、4.186、10.276,P<0.05);不良反应发生率(3.33%)低于参比组(15.00%),差异有统计学意义(χ^(2)=4.904,P<0.05);麻醉效果优良率(96.67%)高于参比组(83.33%),差异有统计学意义(χ^(2)=5.925,P<0.05)。结论针对缺血性脑卒中患者实施介入治疗中,采取盐酸右美托咪定进行麻醉效果突出。
Objective To analyze and study the clinical effects of dexmedetomidine hydrochloride in interventional anesthesia for ischemic stroke.Methods From September 2019 to September 2020,conveniently selected 120 patients with ischemic stroke.Randomly divided into two groups,the study group and the reference group.The study group used conventional general anesthesia and dexmedetomidine hydrochloride,while the reference group only used conventional general anesthesia.A comparative analysis of the clinical effects of the two groups was carried out.Results The APACHEⅡscore(8.41±1.08)points of the study group was lower than that of the reference group,the Steward wake-up score(5.72±0.14)points and the GCS score(14.18±0.63)points were higher than the reference group,the difference was statistically significant(t=19.536,34.637,30.604,P<0.05);heart rate levels at the beginning and end of surgery(84.25±7.16)beats/min,(82.32±6.28)beats/min,blood pressure levels at the beginning and end of surgery(92.24±3.58)mmHg,(90.17±5.24)mmHg were all lower than reference group,the difference was statistically significant(t=9.540,4.078,15.562,4.852,P<0.05);anesthesia recovery time(7.71±1.84)min,operation time(72.58±10.43)min,and extubation time(12.11±1.58)min were shorter than those of the reference group,the difference was statistically significant(t=17.531,4.186,10.276,P<0.05);the incidence of adverse reactions was 3.33%lower than the reference group 15.00%,the difference was statistically significant(χ^(2)=4.904,P<0.05);the excellent and good rate of anesthesia effect was 96.67%higher than that of the reference group 83.33%,the difference was statistically significant(χ^(2)=5.925,P<0.05).Conclusion In the implementation of interventional treatment for patients with ischemic stroke,the anesthesia effect of dexmedetomidine hydrochloride is outstanding.
作者
黄甜甜
李孝争
HUANG Tiantian;LI Xiaozheng(Shanxian Central Hospital,Heze,Shandong Province,274300 China)
出处
《中外医疗》
2022年第2期74-77,共4页
China & Foreign Medical Treatment
关键词
缺血性脑卒中
介入治疗
麻醉
盐酸右美托咪定
临床价值
Ischemic stroke
Interventional therapy
Anesthesia
Dexmedetomidine hydrochloride
Clinical value
