摘要
目的探讨全程健康教育联合气压辅助治疗对膀胱癌术后患者下肢深静脉血栓形成的预防效果。方法依据随机数字表法将110例膀胱癌术后患者分为观察组(n=55)和对照组(n=55),对照组患者予以气压辅助治疗,观察组患者在对照组的基础上予以全程健康教育,两组患者均干预1个月。比较两组患者的下肢深静脉血栓发生情况、凝血指标[D-二聚体(D-D)、活化部分凝血活酶时间(APTT)、血浆纤维蛋白原(FIB)、凝血酶时间(TT)、凝血酶原时间(PT)]、血流动力学指标[红细胞比容(HT)、微循环滞留时间(MST)、红细胞变形系数(TK)]以及健康调查简表(SF-36)评分。结果干预1个月后,观察组患者的下肢深静脉血栓总发生率为1.82%,明显低于对照组患者的16.36%,差异有统计学意义(P﹤0.01)。干预1个月后,观察组患者的D-D、FIB均低于对照组,APTT、TT、PT均短于对照组,HT、TK均低于对照组,MST短于对照组,SF-36各维度评分均高于对照组,差异均有统计学意义(P﹤0.05)。结论全程健康教育联合气压辅助治疗对膀胱癌术后患者下肢深静脉血栓形成的预防效果显著,可有效降低凝血指标,改善血流动力学水平,提高患者生活质量。
Objective To investigate the preventive effect of whole-course health education combined with pneumatic compression adjuvant therapy on lower extremity deep vein thrombosis in patients with bladder cancer after surgery.Method A total of 110 patients with bladder cancer after surgery were divided into observation group(n=55)and control group(n=55)according to the random number table method.Patients in the control group were treated with pneumatic compression adjuvant therapy,and patients in the observation were given whole-course health education based on the treatment of control group,both groups were intervened for 1 month.The incidence of lower extremity deep vein thrombosis,coagulation indexes[D-dimer(D-D),activated partial thromboplastin time(APTT),plasma fibrinogen(FIB),thrombin time(TT),prothrombin time(PT)],hemodynamic indexes[hematocrit(HT),microcirculation stange time(MST),erythrocyte deformation index(TK)],and the MOS item short form healthy survey(SF-36)score were compared.Result After 1 month of intervention,the total incidence of lower extremity deep vein thrombosis in the observation group was 1.82%,which was significantly lower than 16.36%in the control group,and the difference was statistically significant(P<0.01).After 1 month of intervention,the D-D and FIB of patients in the observation group were lower than those of the control group,the APTT,TT and PT were shorter than those of the control group,the HT and TK were lower than those of the control group,the MST was shorter than that of the control group,and the scores of each dimension of SF-36 were higher than those of the control group,the differences were statistically significant(P<0.05).Conclusion Whole-course health education combined with pneumatic compression adjuvant therapy has a remarkable preventive effect on lower extremity deep vein thrombosis in patients with bladder cancer after surgery,which can effectively reduce coagulation indicators,improve hemodynamics and patients’quality of life.
作者
宋娜娜
郑保良
董艳娟
孙国庆
李雯雯
SONG Na’na;ZHENG Baoliang;DONG Yanjuan;SUN Guoqing;LI Wenwen(Department of Urology,Central Hospital of Jiaozuo Coal Industry(Group)Co.,Ltd,Jiaozuo 454000,He’nan,China)
出处
《癌症进展》
2022年第2期204-207,215,共5页
Oncology Progress
关键词
全程健康教育
气压辅助治疗
膀胱癌
下肢深静脉血栓
预防效果
whole-course health education
pneumatic compression adjuvant therapy
bladder cancer
lower extremity deep vein thrombosis
preventive effect
