摘要
探讨氯吡格雷联合阿托伐他汀治疗脑梗死的临床效果。选取81例脑梗死患者为研究对象,随机分为抗血小板组(40例)和他汀组(41例)。抗血小板组给予氯吡格雷治疗,他汀组在此基础上增加阿托伐他汀治疗,对比两组患者的血脂异常情况及神经功能缺损改善效果。他汀组治疗后的NIHSS(14.97±5.67)分显著低于抗血小板组(19.52±4.98)分,甘油三酯(1.06±0.28 mmol/L)、总胆固醇指标(3.49±1.42 mmol/L)显著低于抗血小板组(1.29±0.37 mmol/L、4.28±1.02 mmol/L)(P<0.05)。联合用药可以更好地改善脑梗死患者的血脂水平和神经功能缺损,促进脑梗死预后。
The study explores the clinical effect of clopidogrel combined with atorbastatin treatment on cerebral infarction.81 patients with cerebral infarction are selected as the research objects,and they are randomly divided into antiplatelet group(40 patients)and statin group(41 patients).Antiplatelet group receive clopidogrel treatment,and statin group receive atorvastatin treatment based on antiplatelet group.Dyslipidemia situation and the improvement effect of neurologic impairment of two groups are compared.After treatment,NIHSS,triglyceride,total cholesterol of statin group are(14.97±5.67)points,(1.06±0.28 mmol/L)and(3.49±1.42 mmol/L),which are significantly lower than(19.52±4.98)points,(1.29±0.37)mmol/L and(4.28±1.02)mmol/L of antiplatelet group(P<0.05).Drug combination can better improve the blood lipid level and neurologic impairment of patients,and improve the prognosis of cerebral infarction.
作者
陈瑞
Chen Rui(Heilongjiang Agricultural Reclamation Bei’an Administration Central Hospital, Bei’an 164000, China)
出处
《黑龙江科学》
2022年第4期96-97,共2页
Heilongjiang Science
关键词
氯吡格雷
阿托伐他汀
脑梗死
神经功能缺损
血脂
甘油三酯
总胆固醇
Clopidogrel
Atovastatin
Cerebral infarction
Neurologic impairment
Blood fat
Triglyceride
Total cholesterol
