摘要
目的研究围绝经期异常子宫出血(AUB)的治疗上,曼月乐和安宫黄体酮的治疗效果。方法本文于本院AUB患者中随机选择60例,分成两组,A组使用安宫黄体酮治疗,B组使用曼月乐治疗,对比两组的治疗效果。结果经本文研究,B组患者治疗后E2(225.84±16.84)pmol/L,FSH(10.01±1.02)U/L,LH(9.87±0.47)U/L。B组子宫内膜厚度(5.21±1.34)mm,Hb(115.36±15.38)g/L,Hct(36.42±2.16)%。B组阴道异常出血1例(3.33%),头晕1例(3.33%),无其他不良反应,与A组对比,差异显著(P<0.05)。结论安宫黄体酮治疗AUB患者可取得良好止血效果,但无法治疗严重贫血患者,且药物不良反应相对较多。和安宫黄体酮治疗效果相比,曼月乐治疗效果更加突出,其不良反应较少,能有效抑制血管增生等情况,让子宫内膜加速变薄,改善出血量过多的情况,值得临床广泛应用。
Objective To study the therapeutic effects of Mirena and Progesterone in the treatment of abnormal uterine bleeding(AUB)during perimenopausal period.Methods In this article,60 patients with AUB in our hospital were randomly selected and divided into two groups.Group A was treated with medroxyprogesterone and group B was treated with Mirena.The treatment effects of the two groups were compared.Results According to the study in this article,after treatment,patients in group B have E2(225.84±16.84)pmol/L,FSH(10.01±1.02)U/L,and LH(9.87±0.47)U/L.The thickness of the endometrium in group B was(5.21±1.34)mm,Hb(115.36±15.38)g/L,and Hct(36.42±2.16)%.There was 1 case of abnormal vaginal bleeding in group B(3.33%),and 1 case of dizziness(3.33%).There were no other adverse reactions,compared with group A,the difference was significant(P<0.05).Conclusion An oxyprogesterone can achieve a good hemostatic effect in patients with AUB,but it cannot treat patients with severe anemia,and there are relatively many adverse drug reactions.Compared with the therapeutic effect of medroxyprogesterone,the therapeutic effect of Mirena is more prominent,with fewer adverse reactions,can effectively inhibit vascular proliferation and other conditions,accelerate the thinning of the endometrium,and improve the excessive bleeding.It is worthy of clinical practice widely used.
作者
赵雪
ZHAO Xue(Department of Obstetrics and Gynecology,Dalian Hospital,Shengjing Hospital Affiliated to China Medical University,Dalian 116600,China)
出处
《中国医药指南》
2022年第7期83-85,共3页
Guide of China Medicine
关键词
围绝经期
异常子宫出血
安宫黄体酮
曼月乐
治疗效果
Perimenopausal period
Abnormal uterine bleeding
Medroxyprogesterone
Mirena
Therapeutic effect
