摘要
近年研究显示代谢相关性脂肪性肝病(metabolic associated fatty liver disease,MAFLD)在体质指数(body mass index,BMI)正常的人群中发病率并不低,但尚未受到应有重视。而BMI正常的MAFLD并非既往认为的良性疾病,它不仅具有与肥胖MAFLD患者相似的代谢紊乱、临床表现、并发症,同时在这些方面还有自己的特点,因此应当给予更多关注。本文将围绕BMI正常的MAFLD的发病机制、临床表现、预后和治疗等方面的特点做一综述,以期为个体化MAFLD治疗提供新的思路。
Recent studies have shown a high incidence rate of metabolic associated fatty liver disease(MAFLD) in people with normal body mass index(BMI),which has not been taken seriously in clinical practice. MAFLD with normal BMI is not the benign disease it was thought to be in the past;it not only has similar metabolic disorders,clinical manifestations,and complications to obese MAFLD patients,but also has its own features in these aspects,and therefore,it should be taken seriously in clinical practice. This article summarizes the features of MAFLD with normal BMI from the perspectives of pathogenesis,clinical manifestations,prognosis,and treatment,in order to provide a new idea for individualized treatment of MAFLD.
作者
雷小维(综述)
张利莉(审校)
LEI Xiaowei(reviewing);ZHANG Lili(checking)(Department of Endocrinology,the Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China)
出处
《西南医科大学学报》
2022年第2期172-175,共4页
Journal of Southwest Medical University
基金
国家自然科学基金项目(81300702)
重庆市科委自然科学基金项目(cstc2018jcyjAX0210)。
关键词
代谢相关性脂肪性肝病
BMI正常人群
特点
Metabolic associated fatty liver disease
Patient with normal body mass index
Features
