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临床药师对1例抗结核药物性肝损伤患者的药学干预及监护 被引量:2

Pharmaceutical intervention and monitoring of a patient with anti-tuberculosis drug-induced liver injury by clinical pharmacists
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摘要 目的为临床药师参与抗结核药物性肝损伤后患者再次启动抗结核方案制订提供参考依据。方法临床药师参与抗结核药物性肝损伤患者抗结核药物治疗过程,分析导致患者出现药物性肝损伤的抗结核药物,对患者再次抗结核治疗用药进行安全性评估,并制订肝功能恢复后下一步抗结核药物治疗方案。结果临床药师在治疗过程中协助医生制订了肝功能恢复后再次抗结核治疗的方案,患者结核得到有效控制,且未再出现肝功能损害。结论临床药师参与患者药学干预及监护,保障了患者用药安全有效。 Objective To provide a reference for clinical pharmacists to participate in the formulation of the anti-tuberculosis drug treatment again in patients with anti-tuberculosis drug-induced liver injury.Methods Clinical pharmacists participated in the process of anti-tuberculosis drug treatment in the patient with anti-tuberculosis drug-induced liver injury,analyzed the anti-tuberculosis drugs that could lead to drug-induced liver injury,evaluated the safety of the anti-tuberculosis treatment for the patients,and determined the next anti-tuberculosis drug treatment plan after the recovery of liver function.Results The clinical pharmacist assisted the doctor in formulating the plan for re-anti-tuberculosis treatment after the recovery of liver function for the patient during treatment.At last,the tuberculosis of the patient was effectively controlled and no further liver function damage occurred.Conclusion Clinical pharmacists participated in the pharmaceutical intervention and monitoring,and ensure the safety and effective drug use of patients.
作者 谭瑞 李晶 孙伟 TAN Rui;LI Jing;SUN Wei(Department of Pharmacy,People′s Hospital of Ba′nan District,Chongqing 401320,China;Department of Infectious Diseases,People′s Hospital of Ba′nan District,Chongqing 401320,China)
出处 《重庆医学》 CAS 2022年第6期978-981,共4页 Chongqing medicine
基金 重庆市科卫联合医学科研项目(2022QNXM003)。
关键词 抗结核药 药物性肝损伤 抗结核化疗原则 药学干预 临床药师 antituberculotic drug drug-induced liver injury chemotherapy principle for tuberculosis pharmaceutical intervention clinical pharmacists
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