摘要
目的回顾性分析长效长方案治疗的辅助生殖技术助孕后的母亲妊娠结局和子代(1岁内)健康状况,探讨粤西地区辅助生殖技术的安全性。方法以2013—2016年广东医科大学附属医院生殖医学中心长效长方案患者共680个周期,407个胎儿为对象,分析妊娠结局及子代(1岁内)发育情况。结果卵胞质内单精子注射(ICSI)组发生妊娠并发症多于体外受精(IVF)组,女性子代更多;多胎组与单胎组比较,低体重儿及早产儿出生率高。结论 ICSI会增加妊娠并发症及女性子代比例,多胎妊娠增加早产率及低出生体重发生率,而新鲜胚胎和冻融胚胎移植妊娠结局无差异。
Objective Retrospective analysis of the long-term treatment of assisted reproductive technology in the mother’s pregnancy outcome and the health status of the offspring(within 1 year old) to explore the safety of assisted reproductive technology. Methods From 2013 to 2016, the long-term program of the Reproductive Center of the Affiliated Hospital of Guangdong Medical University, a total of 680 cycles, 407 fetuses were collected, and analysis of their fertility treatment were analyzed. After the outcome and the successful development of the ART(within 1 year old) and the presence of malformations. Results In the ICSI(intracytoplasmic sperm injection) group, pregnancy complications and female offsprin were more than in the IVF(in vitro fertilization) group;compared with the single-fetal group, the multi-child group has a high birth rate in low-weight children and premature infants. Conclusion Compared with the IVF group, ICSI increased pregnancy complications and the proportion of female offspring. Multiple pregnancies increased preterm birth rate and low birth weight,while there was no difference in pregnancy outcome between fresh embryo and frozen embryo transfer.
作者
黄巧瑶
梁晓
游慧娴
周小花
吴小环
马天仲
HUANG Qiaoyao;LIANG Xiao;YOU Huixian;ZHOU Xiaohua;WU Xiaohuan;MA Tianzhong(Center for Reproductive Medicine,Affiliated Hospital of Guangdong Medical University,Zhanjiang,Guangdong 524001,China;Department of Internal Medicine,Affiliated Hospital of Guangdong Medical University,Zhanjiang,Guangdong 524001,China)
出处
《中国优生与遗传杂志》
2022年第2期259-264,共6页
Chinese Journal of Birth Health & Heredity
基金
湛江市科技发展专项资金竞争性分配项目(2019A01023)。
关键词
辅助生殖技术
母亲妊娠结局
子代健康状况
assisted reproductive technology
maternal pregnancy outcomes
offspring health
