微循环障碍对ST段抬高心肌梗死直接经皮冠状动脉介入治疗术后患者左心室舒张功能的影响被引量：5

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摘要目的探索ST段抬高心肌梗死直接经皮冠状动脉介入治疗(primary percutaneous coronary intervention,PPCI)术后微循环障碍对左心室舒张功能的影响。方法选取2017年1月至2018年1月92例于河北省秦皇岛市第一医院行PPCI的ST段抬高心肌梗死患者,依据支架术后即刻血流分级心肌灌注帧数评分将患者分为合并微循环障碍的观察组和无微循环障碍的对照组,观察并比较两组患者临床基线参数和超声舒张功能指标:二尖瓣舒张早期血流速度(E峰)、二尖瓣舒张晚期血流速度(A峰)、二尖瓣环舒张期运动速度(e’)、左心房容积指数并计算E/A、E/e’,观察患者PPCI术后1周及3个月左心室舒张功能变化。结果对照组E峰、E/A、e’于3个月复查时较1周时显著升高,而E/e’较1周时显著降低(P<0.05);观察组术后3个月时左心房容积指数较1周时显著增高,差异有显著性(P<0.05);观察组Ⅱ级、Ⅲ级左心室舒张功能患者比例明显高于对照组(P<0.05);E/e’同心肌灌注帧数具有显著相关性(r=0.852,P<0.05)。结论微循环障碍可导致急性心肌梗死患者PPCI术后左心室舒张功能减低且恢复不良,微循环障碍与左心室舒张功能明显相关。

作者刘雅婷赵甲彧刘丽蒋文军赵恒达张芳

机构地区河北省秦皇岛市第一医院超声科河北省秦皇岛市第一医院心内科

出处《中国临床医生杂志》 2022年第4期426-429,共4页 Chinese Journal For Clinicians

基金河北省秦皇岛市重点研发计划科技支撑项目(201805A059)。

关键词 ST段抬高心肌梗死经皮冠状动脉介入治疗即刻血流分级心肌灌注帧数左心室舒张功能微循环障碍

分类号 R541 [医药卫生—心血管疾病]

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