摘要
目的观察丙泊酚联合穴位电刺激对食管癌术后患者肺功能及炎症状态的影响。方法将我院70例食管癌患者随机分为观察组与对照组各35例。观察组术中采用丙泊酚联合穴位电刺激麻醉,对照组术中采用丙泊酚麻醉,比较两组麻醉效果,手术前后肺功能、炎症因子、苏醒拔管时间和镇痛评分。结果术后,观察组麻醉优良率显著高于对照组(P<0.05);两组每分钟最大通气量/预计值百分比(MVV%)、第1秒用力呼气容积占预计值百分比(FEV1%)均下降,且观察组下降幅度低于对照组(P<0.05);两组白介素-6(IL-6)、白介素-1(IL-1)表达均增加,且观察组增加幅度低于对照组(P<0.05);观察组拔管后10min苏醒评分高于对照组,镇静评分低于对照组(P<0.05)。结论丙泊酚联合穴位电刺激对食管癌患者麻醉效果较满意,能改善术后肺功能和炎症状态,促进麻醉恢复。
Objective To observe the effect of propofol combined with acupoint electrical stimulation on lung function and inflammation in patients after esophageal cancer surgery.Methods 70 patients with esophageal cancer were randomly divided into observation group and control group with 35 cases each.Control group was anesthetized with propofol during the operation,and observation group was anesthetized with acupoint electrical stimulation on the basis of control group.The effects of anesthesia,lung function,inflammatory factors,recovery time and analgesia score were compared between the two groups before and after surgery.Results After surgery,the excellent and good rate of anesthesia in observation group was higher than control group(P<0.05).Maximum ventilation per minute/Percent of predicted value(MVV%),forced expiratory volume in 1 second percentage of predicted value(FEV1%)of both groups decreased;the decreases in observation group were more obvious than control group(P<0.05);interluekin-6(IL-6)and IL-1 increased in both groups,the increases in observation group were more obvions than control group(P<0.05);the awakening score of observation group 10 min after extubation was higher than control group,and the sedation score was lower than control group(P<0.05).Conclusion Propofol combined with acupoint electrical stimulation is satisfactory for the anesthesia effect of patients with esophageal cancer,which can improve the postoperative lung function and inflammation,and promote recovery from anesthesia.
作者
赵璐
涂红霞
聂坤芹
ZHAO Lu;TU Hong-xia;NIE Kun-qin(Ba'nan District People's Hospital of Chongqing,Chongqing 401320;Qijiang Hospital of the First Affiliated Hospital of Chongqing Medical University/People's Hospital of Chongqing Qijiang District,Chongqing 401420)
出处
《湖北中医药大学学报》
2022年第1期109-111,共3页
Journal of Hubei University of Chinese Medicine
基金
重庆市卫生健康委员会2019年市级中医药重点学科(针灸推拿学)基金资助项目(项目编号:201843)。
关键词
食管癌
丙泊酚
穴位电刺激
肺功能
炎症状态
Esophageal cancer
Propofol
Electrical acupoint stimulation
Lung function
Inflammatory state
