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溃疡性结肠炎中医证候及其生物标记物研究进展 被引量:10

Research Progress of TCM Syndromes and Biomarkers of Ulcerative Colitis
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摘要 溃疡性结肠炎(ulcerative colitis,UC)在中医上隶属于"泄泻""肠澼""痢疾"等多个范畴。中医将其分属为多个证候类型,每个证候类型各有其证候特点、规律。辨证论治是中医对溃疡性结肠炎病情的实时把控,是提高溃疡性结肠炎疗效的关键所在。生物标记物是个体对内外界刺激所作出的生物学介质的改变。生物学介质与溃疡性结肠炎的中医证候有一定的关联性,其可能是实现溃疡性结肠炎中医证候诊断量化、标准化的关键。通过对中医证型、证候、肠镜表现、细胞学及肠道菌群等方面论述溃疡性结肠炎的中医证候及客观参考指标的研究进展,以期为溃疡性结肠炎中医证候诊断的量化、标准化、客观化提供依据,从而提高临床诊疗能力,以此为今后更深层次的研究提供依据。 Ulcerative colitis(UC)in Chinese medicine belongs to category such as“diarrhea”.Traditional Chinese medicine divides its syndrome differentiation into multiple syndrome types,and each syndrome type has its own syndrome characteristics and laws.Syndrome differentiation and treatment is the real-time control of ulcerative colitis by traditional Chinese medicine,and is the key to improving the efficacy of ulcerative colitis.Biomarkers are the changes of biological media made by individuals to internal and external stimuli.There is a certain correlation between biological media and TCM syndromes of ulcerative colitis,which may be the key to realizing the quantification and standardization of TCM syndrome diagnosis of ulcerative colitis.Discussing the research progress of TCM syndromes and objective reference indicators of ulcerative colitis through the aspects of TCM syndromes,syndromes,colonoscopy manifestations,cytology and intestinal flora,to quantify,standardize,and objectively diagnose TCM syndromes of ulcerative colitis,so as to improve the clinical diagnosis and treatment capabilities,and provide a basis for deeper research in the future.
作者 吴毅娟 郭海霞 孙兴红 张相安 WU Yijuan;GUO Haixia;SUN Xinghong;ZHANG Xiang'an(Henan University of Chinese Medicine,Zhengzhou 450046,Henan,China;The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,Henan,China)
出处 《辽宁中医药大学学报》 CAS 2022年第2期136-140,共5页 Journal of Liaoning University of Traditional Chinese Medicine
基金 河南省中医药科研专项(2017ZY2058) 河南省科技攻关项目(182102310289)。
关键词 溃疡性结肠炎 中医 证候 生物标记物 ulcerative colitis Chinese medicine syndromes biomarkers
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