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连续性静脉-静脉血液滤过治疗急性重度有机磷农药中毒的效果观察 被引量:2

Observation on the Effect of Continuous Venous-Venous Hemofiltration in the Treatment of Acute Severe Organophosphorus Pesticide Poisoning
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摘要 目的 探讨连续性静脉-静脉血液滤过(CVVH)治疗急性重度有机磷农药中毒(ASOPP)的临床效果。方法 回顾性分析2017年1月至2020年2月我院收治的70例ASOPP患者的临床资料,对照组(37例)行常规治疗,观察组(33例)在对照组基础上行CVVH。比较两组患者的氯解磷定总用量、长托宁总用量、住院时间与呼吸机支持时间。结果 观察组的氯解磷定总用量、长托宁总用量均低于对照组(P<0.05)。观察组的呼吸机支持时间、住院时间均短于对照组(P<0.05)。结论 CVVH治疗ASOPP的效果显著,可有效降低氯解磷定与长托宁的使用剂量,缩短患者的住院时间及呼吸机支持时间。 Objective To explore the clinical effect of continuous venous-venous hemofiltration(CVVH) in the treatment of acute severe organophosphorus pesticide poisoning(ASOPP). Methods The clinical data of 70 ASOPP patients admitted to our hospital from January 2017 to February 2020 were retrospectively analyzed. The control group(37 cases) received conventional treatment, and the observation group(33 cases) received CVVH on the basis of the control group. The total dosage of pralidoxime chloride, total dosage of penehyclidine hydrochloriden, hospitalization time and ventilator support time were compared between the two groups. Results The total dosage of pralidoxime chloride and penehyclidine hydrochloriden in the observation group were lower than those in the control group(P<0.05). The ventilator support time and hospitalization time of the observation group were shorter than those of the control group(P<0.05).Conclusions CVVH has significant effect in the treatment of ASOPP, which can effectively reduce the dosage of pralidoxime chloride and penehyclidine hydrochloriden, and shorten the hospitalization time and ventilator support time.
作者 孙新帅 杜艳征 SUN Xinshuai;DU Yanzheng(Department of Emergency,Luoyang Central Hospital Affiliated to Zhengzhou University,Luoyang 471000,China)
出处 《临床医学工程》 2022年第3期369-370,共2页 Clinical Medicine & Engineering
关键词 连续性静脉-静脉血液滤过 急性重度有机磷农药中毒 临床效果 Continuous venous-venous hemofiltration Acute severe organophosphorus pesticide poisoning Clinical effect
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