摘要
目的:观察择时耳穴压豆治疗缺血性脑卒中后失眠的临床疗效。方法:临床纳入97例缺血性脑卒中后失眠患者,随机分为对照组(47例)和耳穴组(50例),治疗4周。观察入睡潜伏期、觉醒次数、实际睡眠时间、睡眠效率改善情况,匹兹堡睡眠质量指数(PSQI)量表及汉密尔顿焦虑量表(HAMD)积分,血清脑源性神经营养因子(BDNF)的变化。结果:治疗后与对照组比较,耳穴组入睡潜伏期、觉醒次数显著减少(P<0.01),实际睡眠时间和睡眠效率显著增加(P<0.01);PSQI积分、HAMD积分显著降低(P<0.05),血清BDNF显著升高(P<0.05)。结论:择时耳穴压豆对脑卒中后失眠患者的疗效优于艾司唑仑。
Objective: To evaluate the clinical effects of ear pressure beans with choosing time treatment for post ischemic stroke insomnia patients. Methods: A total of 97 cases of ischemic stroke patients with insomnia who met the standard were randomly divided into control group(47 cases) and ear pressure beans group(50 cases). After 4 weeks of choosing time treatment with ear pressure beans, effects were evaluated with sleep onset latency, awakening number, actual sleep time and sleep efficiency, Pittsburgh Sleep Quality Index(PSQI), Hamilton Depression Scale(HAMD), serum brain-derived neurotrophic factor(BDNF). Results: After the 4-week treatment, compared with the control group, sleep onset latency and awakening number in ear pressure beans group were significantly decreased(P<0.01), actual sleep time and sleep efficiency in ear pressure beans group were significantly increased(P<0.01), PSQI and HAMD scale were significantly decreased(P<0.05), and serum BDNF was significantly increased(P<0.05). Conclusion: The efficacy of ear pressure beans with choosing time treatment is more effective than Estazolam for post stroke insomnia patients.
作者
张华军
岳丽军
马倩
徐天舒
ZHANG Hua-jun;YUE Li-jun;MA Qian;XU Tian-shu(Department of Traditional Chinese Medicine,Nanjing Drum Tower Hospital,Medical School of Nanjing University,Nanjing 210008,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2022年第2期1198-1200,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
十三五南京市卫生青年人才培养工程项目(No.QRX17043)。
关键词
择时治疗
耳穴压豆
缺血性脑卒中
失眠
Choosing time treatment
Ear pressure beans
Post ischemic stroke
Insomnia
