摘要
目的探讨对小儿重症肺炎患者采用纤维支气管镜肺泡灌洗方法治疗后获得的临床疗效以及安全性。方法选取2019年1月1日—2020年12月31日收治的92例小儿重症肺炎患者进行治疗研究;采用数字奇偶法分为常规组(基础治疗)和研究组(基础治疗+纤维支气管镜肺泡灌洗治疗),各46例;比较两组患儿治疗总有效率、肺功能指标[第1秒用力呼气容积(forced expiratory volume in the first second,FEV_(1))、用力肺活量(forced vital capacity,FVC)]、动脉血气分析指标[动脉血氧分压(arterial partial pressure of oxygen,PaO_(2))、血氧饱和度(blood oxygen saturation,SaO_(2))、动脉血二氧化碳分压(arterial partial pressure of carbon dioxide,PaCO_(2))]、血清炎症因子指标[C反应蛋白(C-reactive protein,CRP)、降钙素原(procalcitonin,PCT)、白细胞计数(white blood cell count,WBC)]、并发症(剧烈咳嗽、窦性心动过速、窦性心动过缓)总发生率。结果研究组治疗总有效率(95.65%)高于常规组(76.09%),差异有统计学意义(P<0.05);研究组FEV_(1)水平、FVC水平高于常规组,差异有统计学意义(P<0.05);研究组PaO_(2)、SaO_(2)水平均高于常规组,PaCO_(2)水平低于常规组,差异有统计学意义(P<0.05);研究组CRP、PCT、WBC水平均低于常规组,差异有统计学意义(P<0.05);研究组并发症总发生率(2.17%)同常规组(4.35%)比较,差异无统计学意义(P>0.05)。结论纤维支气管镜肺泡灌洗方法有效应用后,在保证治疗安全性前提下,可促进小儿重症肺炎患者临床疗效、预后水平提升。
Objective To investigate the clinical efficacy and safety of alveolar lavage by fiberoptic bronchoscope in the treatment of children with severe pneumonia.Methods A total of 92 pediatric patients with severe pneumonia from January 1,2019 to December 31,2020 were selected for the treatment study.The patients were divided into two groups by odd-even method:routine treatment group(basic treatment)and study group(basic treatment+bronchoscopic alveolar lavage),46 cases in each group.The total effective rate,pulmonary function indexes[forced expiratory volume in the first second(FEV_(1)),forced vital capacity(FVC)],arterial blood gas analysis indexes[arterial partial pressure of oxygen(PaO_(2)),blood oxygen saturation(SaO_(2)),arterial partial pressure of carbon dioxide(PaCO_(2))],serum inflammatory factors indexes[C-reactive protein(CRP),procalcitonin(PCT),white blood cell count(WBC)],complications incidence rate(severe cough,sinus tachycardia,sinus bradycardia).Results The total effective rate of study group(95.65%)was higher than that of conventional group(76.09%),the difference was statistically significant(P<0.05).The levels of FEV_(1) and FVC in the study group were higher than those in the conventional group,the difference was statistically significant(P<0.05).The levels of PaO_(2) and SaO_(2) in the study group were higher than those in the conventional group,while the PaCO_(2) level was lower than that in the conventional group,the difference was statistically significant(P<0.05).The levels of CRP,PCT and WBC in the study group were lower than those in the conventional group,the difference was statistically significant(P<0.05).The total incidence of complications in the study group(2.17%)was not significantly different from that in the conventional group(4.35%),the difference was not statistically significant(P>0.05).Conclusion The effective application of alveolar lavage by fiberoptic bronchoscope can improve the clinical efficacy and prognosis of pediatric patients with severe pneumonia on the premise of ensuring the safety of treatment.
作者
董娜
DONG Na(Department of Pediatrics,Chifeng Municipal Hospital,Chifeng Inner Mongolia 024000,China)
出处
《中国卫生标准管理》
2022年第5期22-25,共4页
China Health Standard Management
关键词
小儿重症肺炎
纤维支气管镜肺泡灌洗
疗效
肺功能指标
动脉血气分析指标
血清炎症因子指标
并发症
children with severe pneumonia
alveolar lavage by fiberoptic bronchoscope
curative effect
lung function index
arterial blood gas analysis index
serum inflammatory cytokines
complications
