摘要
目的 评析对非侵袭性真菌性鼻窦炎患者在医治过程中使用鼻内镜手术联合低温等离子射频消融术的临床应用意义。方法此研究随机选取的116例非侵袭性真菌性鼻窦炎患者选取时间为2018年6月—2020年6月,分为使用低温等离子射频消融术的对照组(n=58)和加用鼻内镜手术的试验组(n=58),比较治疗前后患者鼻腔通气状况、血清炎性介质含量及治疗有效性。结果 治疗前鼻阻力(左右鼻腔阻力)差异无统计学意义(P> 0.05),治疗后,试验组患者鼻阻力低于单用低温等离子射频消融术的对照组,差异有统计学意义(P <0.05);且治疗后的试验组血清炎性介质水平(IL-5和TNF-α)显著好于对照组,差异有统计学意义(P<0.05);试验组治疗总有效率更高,数据对比差异有统计学意义(P <0.05)。试验组患者的并发症发生率明显低于对照组,经对比两组之间差异有统计学意义(P <0.05)。结论 对非侵袭性真菌性鼻窦炎患者治疗时同时使用鼻内镜手术和低温等离子射频消融术能够切实改善治疗效果,促进患者机体炎症水平降低并有效改善患者鼻腔通气状态。
Objective To evaluate the clinical application significance of endoscopic sinus surgery combined with low-temperature plasma radiofrequency ablation in the treatment of patients with non-invasive fungal sinusitis. Methods A total of 116 randomly selected patients with non-invasive fungal sinusitis in this study were selected from June 2018to June 2020, and were divided into a control group(n=58) using lowtemperature plasma radiofrequency ablation, in the experimental group combined with endoscopic sinus surgery(n =58), the patient’s nasal ventilation status, serum inflammatory media content and treatment effectiveness were compared before and after treatment. Results There was no statistically significant difference in nasal resistance(left and right nasal cavity resistance) before treatment(P > 0.05). After treatment, the nasal resistance in the experimental group was lower than that in the control group, the difference was statistically significant(P < 0.05);and after treatment, the levels of serum inflammatory mediators(IL-5 and TNF-α) in the experimental group were significantly better than those in the control group, the difference was statistically significant(P < 0.05);the experimental group had a higher overall effective rate of treatment, the difference was statistically significant(P < 0.05). The complication rate of the experimental group was significantly lower than that of the control group, the difference was statistically significant(P <0.05). Conclusion The simultaneous use of endoscopic sinus surgery and low-temperature plasma radiofrequency ablation in the treatment of patients with non-invasive fungal sinusitis can effectively improve the treatment effect, promote the reduction of the patient’s body inflammation and effectively improve the patient’s nasal ventilation.
作者
王崇辉
丁翠红
江志娟
WANG Chonghui;DING Cuihong;JIANG Zhijuan(Department of Otolaryngology,People’s Hospital of Jimo District,Qingdao Shandong 266200,China;Department of Otolaryngology,Jimo Hospital of Traditional Chinese Medicine,Qingdao Shandong 266200,China)
出处
《中国卫生标准管理》
2022年第5期48-51,共4页
China Health Standard Management
关键词
鼻内镜手术
低温等离子射频消融术
非侵袭性真菌性鼻窦炎
临床分析
效果
应用意义
endoscopic sinus surgery
low-temperature plasma radiofrequency ablation
non-invasive fungal sinusitis
clinical analysis
effect
application significance
