摘要
水凝胶农药缓释制剂是当前农药制剂研究的热点之一。以羧甲基壳聚糖(CMCS)和丙硫菌唑为主要原料,以金属锰离子(Mn^(2+))为交联剂,采用乳化交联的方法制备了CMCS-丙硫菌唑缓释复合水凝胶微球。以水凝胶微球的成球性、载药率和包封率为指标,采用单因素试验法筛选出较为适宜的制备条件,并通过盆栽试验,研究了丙硫菌唑水凝胶微球在土壤、小麦根部和地上部中的时空分布。试验结果表明,CMCS-丙硫菌唑水凝胶微球最适制备条件:乳化剂Tween-80质量分数为2%,CMCS质量分数为4%,交联剂浓度为0.2 mol/L,油水比为1∶10(V/V)。所得丙硫菌唑缓释复合水凝胶微球的载药率为22.17%±0.83%,包封率为68.37%±2.56%。丙硫菌唑水凝胶微球有助于降低丙硫菌唑在土壤、小麦植株中的脱硫代谢转化,有望提升丙硫菌唑的应用性能。
Hydrogel-based sustained-release formulations of pesticides are one of the current hotspots in the research of pesticide formulations.Taking carboxymethyl chitosan(CMCS)and prothioconazole as the main raw materials,and metal manganese ion(Mn^(2+))as the cross-linking agent,the sustained-release hydrogel microspheres of CMCS-prothioconazole were prepared by the emulsified cross-linking method.Based on the spheroidization,pesticide loading efficiency and encapsulation efficiency of hydrogel microspheres,a single factor experiment was used to screen out the suitable preparation conditions.Furthermore,the temporal and spatial distribution of prothioconazole hydrogel microspheres in soil,wheat roots and aerial parts were studied via pot experiments.The results showed that the mass fraction of emulsifier Tween-80 was 2%.The mass fraction of CMCS was 4%.The concentration of cross-linking agent was 0.2 mol/L.The ratio of oil-water was 1:10(V/V).Under the optimized conditions,the prothioconazole loading content and encapsulation efficiency of the obtained prothioconazole hydrogel microspheres were 22.17%±0.83%and 68.37%±2.56%,respectively.The prothioconazole hydrogel microspheres contributed to reduce the desulfurization metabolic conversion of prothioconazole in soil and wheat plants,which was expected to improve the application performance of prothioconazole.
作者
许春丽
曹立冬
李远播
黄啟良
XU Chunli;CAO Lidong;LI Yuanbo;HUANG Qiliang(Institute of Plant Protection,Chinese Academy of Agricultural Sciences,Beijing 100193,China)
出处
《现代农药》
CAS
2022年第2期26-31,36,共7页
MODERN AGROCHEMICALS
基金
中央级公益性科研院所基本科研业务费(Y2020XK14)。
关键词
水凝胶
羧甲基壳聚糖
丙硫菌唑
单因素试验
时空分布
小麦
hydrogel
carboxymethyl chitosan
prothioconazole
single factor experiment
spatio-temproal distribution
wheat
