摘要
目的:观察季德胜蛇药片联合连续肾脏替代(CRRT)治疗重症蜂蜇伤的临床疗效。方法:将76例重症蜂蜇伤患者按照随机数字表法分为研究组与对照组各38例,对照组采用CRRT治疗,研究组在对照组基础上加用季德胜蛇药片治疗。疗程结束后比较2组临床疗效、肾功能及生命体征各项指标恢复情况。结果:治疗后,研究组治疗总有效率94.74%,高于对照组73.68%(P<0.05)。与同组治疗前比较,治疗后2组24 h尿量增加(P<0.05),血氧饱和度、中心静脉压、平均动脉压升高(P<0.05),尿酸、血肌酐、尿素氮水平及心率降低(P<0.05);与对照组治疗后比较,研究组治疗后24 h尿量较多(P<0.05),血氧饱和度、中心静脉压、平均动脉压较高(P<0.05),尿酸、血肌酐、尿素氮水平及心率较低(P<0.05)。结论:季德胜蛇药片联合CRRT治疗重症蜂蜇伤疗效显著,可迅速缓解临床症状,恢复生命体征,保护肾功能。
Objective:To observe the clinical effect of the Jidesheng Sheyao tablets combined with continuous renal replacement therapy(CRRT)on severe wasp stings.Methods:A total of 76 patients with severe wasp stings were divided into the study group and the control group according to random number table method,with 38 cases in each group.The control group was treated with CRRT,and the study group was additionally treated with Jidesheng Sheyao tablets based on the treatment of the control group.After treatment,the clinical effect,kidney function and levels of vital signs were compared in the two groups.Results:After treatment,the total effective rate was 94.74%in the study group,higher than that of73.68%in the control group(P<0.05).After treatment,the 24 h urine volume was increased when compared with that before treatment(P<0.05),and the levels of blood oxygen saturation,central venous pressure and mean arterial pressure were increased(P<0.05),and the levels of uric acid,serum creatinine,urea nitrogen and heart rate were decreased(P<0.05).Compared with those in the control group after treatment,the 24 h urine volume was larger in the study group(P<0.05),and the levels of blood oxygen saturation,central venous pressure and mean arterial pressure were higher,and the levels of uric acid,serum creatinine,urea nitrogen and heart rate were lower(P<0.05).Conclusion:Jidesheng Sheyao tablets combined with CRRT has significant effect on the treatment of severe wasp stings,which can quickly relieve clinical symptoms,restore vital signs and protect the kidney function.
作者
方林军
谢民民
王建军
朱军东
FANG Linjun;XIE Minmin;WANG Jianjun;ZHU Jundong
出处
《新中医》
CAS
2022年第5期124-127,共4页
New Chinese Medicine
关键词
重症蜂蜇伤
季德胜蛇药片
连续肾脏替代疗法
肾功能
Severe wasp stings
Jidesheng Sheyao tablets
Continuous renal replacement therapy
Kidney function
