摘要
目的探讨磁共振T2mapping成像在膝关节骨关节炎(KOA)诊断中的应用价值。方法选取本溪市中心医院2017年1月至2020年12月诊治的KOA患者148例(KOA组)及健康志愿者30例(对照组)的膝关节磁共振图像资料,测量膝关节各亚区软骨的T2值,并进行分组和统计学分析。结果轻度KOA组、重度KOA组中男性与女性膝关节各亚区软骨的T2值差异均无统计学意义(均P>0.05)。对照组胫骨内侧前区、胫骨内侧中区、胫骨内侧后区、胫骨外侧前区、胫骨外侧中区、胫骨外侧后区、股骨内侧中区、股骨内侧后区、股骨外侧中区、股骨外侧后区T2值分别为(44.47±2.35)ms、(46.52±3.12)ms、(45.47±2.40)ms、(43.68±2.12)ms、(46.33±3.36)ms、(43.92±3.42)ms、(43.58±2.40)ms、(45.53±3.91)ms、(44.36±3.15)ms、(46.41±3.04)ms,轻度KOA组分别为(49.56±2.05)ms、(51.67±2.38)ms、(50.47±2.53)ms、(48.68±3.05)ms、(51.33±4.62)ms、(48.92±2.53)ms、(48.58±3.15)ms、(50.53±3.72)ms、(48.36±2.41)ms、(51.41±3.64)ms,重度KOA组分别为(53.47±2.46)ms、(56.52±3.57)ms、(54.85±2.89)ms、(52.68±3.57)ms、(56.33±3.91)ms、(52.92±3.04)ms、(53.58±3.36)ms、(55.53±3.42)ms、(52.36±4.13)ms、(56.41±3.56)ms,三组差异均有统计学意义(F=38.768、39.412、38.981、40.432、38.416、38.635、38.347、40.712、38.158、39.418,均P<0.05)。结论KOA患者膝关节软骨T2值与性别无关,与疾病严重程度有关,磁共振T2mapping成像用于KOA诊断能起到一定程度分级作用,并可发现早期KOA患者软骨成分的变化。
Objective To investigate the application value of magnetic resonance T2mapping in the diagnosis of knee osteoarthritis(KOA).Methods The MRI data of the knees of 148 patients with KOA who underwent diagnosis and treatment between January 2017 and December 2020 in Benxi Central Hospital(KOA group)and 30 healthy volunteers(control group)were retrospectively analyzed.T2 values of cartilage in each sub-region of the knee were measured,grouped,and statistically analyzed.Results There was no significant difference in the T2 value of cartilage in each sub-region of the knee between male and female patients in mild and severe KOA groups(all P>0.05).T2 values in the medial anterior,middle,and posterior areas of the tibia,lateral anterior,middle and posterior areas of the tibia,medial middle,posterior and lateral areas of the femur,and lateral posterior area of the femur were(44.47±2.35)ms,(46.52±3.12)ms,(45.47±2.40)ms,(43.68±2.12)ms,(46.33±3.36)ms,(43.92±3.42)ms,(43.58±2.40)ms,(45.53±3.91)ms,(44.36±3.15)ms,(46.41±3.04)ms,respectively in the control group.They were(49.56±2.05)ms,(51.67±2.38)ms,(50.47±2.53)ms,(48.68±3.05)ms,(51.33±4.62)ms,(48.92±2.53)ms,(48.58±3.15)ms,(50.53±3.72)ms,(48.36±2.41)ms,and(51.41±3.64)ms,respectively in the mild KOA group,and(53.47±2.46)ms,(56.52±3.57)ms,(54.85±2.89)ms,(52.68±3.57)ms,(56.33±3.91)ms,(52.92±3.04)ms,(53.58±3.36)ms,(55.53±3.42)ms,(52.36±4.13)ms,and(56.41±3.56)ms,respectively in the severe KOA group.There were significant differences in abovementioned indices among the three groups(F=38.768,39.412,38.981,40.432,38.416,38.635,38.347,40.712,38.158,39.418,all P<0.05).Conclusion The T2 value of knee cartilage in patients with KOA is unrelated to gender and related to the severity of the disease.Magnetic resonance T2 mapping can help diagnose KOA,and provide information about the changes in cartilage components of patients with early KOA.
作者
丁伟
张宁
张宇
陈丽君
罗莎
Ding Wei;Zhang Ning;Zhang Yu;Chen Lijun;Luo Sha(Department of Radiology,Benxi Central Hospital,Benxi 117000,Liaoning Province,China)
出处
《中国基层医药》
CAS
2022年第4期563-566,共4页
Chinese Journal of Primary Medicine and Pharmacy
关键词
骨关节炎
膝
软骨
关节
磁共振成像
弥散张量成像
量化构效关系
T2值
性别因素
诊断
Osteoarthritis,knee
Cartilage,articular
Magnetic resonance imaging
Diffusion tensor imaging
Quantitative structure-activity relationship
T2 value
Sex factors
Diagnosis
