摘要
结合科研成果及实验教学经验,对有机化学实验中传统的甲基化反应实验进行改进。教材中涉及的传统甲基化试剂具有毒性大等缺点,不利于实验教学的实施。因此,提出使用三氟乙酸甲酯取代传统甲基化试剂,应用于本科有机化学实验教学中,加强学生对甲基化反应理论知识的理解。本实验结合新颖的科研内容,引入科研实验的设计思路,不仅有利于学生更好地掌握理论知识,而且有利于激发学生对科学研究的兴趣,提高学生的综合素养。
Combined with scientific research achievements and experimental teaching experience, the traditional experiment of methylation reaction in organic chemistry experiment was improved. The traditional methylation reagents involved in the teaching materials have disadvantage such as high toxicity, which is not conducive to the implementation of experimental teaching. Therefore, this paper proposes to replace traditional methylation reagents with methyl trifluoroacetate from scientific research achievements and applies it to the experimental teaching of organic chemistry for undergraduates, so as to enhance students’ understanding of the theoretical knowledge of methylation reaction. This experiment combines novel scientific research content and introduces the design idea of scientific research experiment, which is not only conducive to students to better grasp the theoretical knowledge of books, but also to stimulate students’ interests in scientific research and improve their comprehensive quality.
作者
肖朵朵
李翠妍
熊敏东
叶华清
曾志威
周建敏
XIAO Duo-Duo;LI Cui-Yan;XIONG Min-Dong;YE Hua-Qing;ZENG Zhi-Wei;ZHOU Jian-Min(College of Chemistry,Guangdong University of Petrochemical Technology,Maoming 525000,China)
出处
《化学教育（中英文）》
CAS
北大核心
2022年第6期83-85,共3页
Chinese Journal of Chemical Education
基金
广东省本科高校教学质量与教学改革工程项目(2017年度综合类)
广东省普通高校青年创新人才项目(2018KQNCX167)
广东石油化工学院人才引进项目(517158)
广东石油化工学院校级重点团队应用物理化学和应用有机化学课程群教学团队(JXTD201922)
2019年度大学生创新创业训练项目(733313,733334)。
关键词
甲基化
有机化学
创新设计性实验
三氟乙酸甲酯
methylation
organic chemistry
innovative design experiment
methyl trifluoroacetate
