摘要
目的:基于文献报道探讨成人新型冠状病毒肺炎(简称新冠肺炎)中医证素分布及组合规律。方法:截至到2020年3月3日,从中国知网、中国生物医学文献数据库、万方数据库和维普网数据库中检索有关新冠肺炎中医证素的文献,并对文献信息进行收集整理,采用SPSS20.0统计软件进行统计描述的分析。结果:33个证素中,病性证素频率依次为湿(82.6%)、疫毒(76.8%)、气虚(76.8%)、阳虚(60.9%)、热(59.4%)、阴虚(43.5%)、寒(40.6%)、血瘀(15.9%)等,病位证素频率依次为肺(100%)、脾(59.4%)、表(14.5%)、卫(14.5%)、胃(13%)、肠(10.1%)、肝(8.7%)、心(8.7%)等;在证素组合中,以3证素及2证素组合最常见,频率为57.7%、15.8%。两证素组合中,疫毒闭肺证(7.4%)、肺气虚证(1.4%)、湿邪犯肺证(1.0%)出现频率较高;三证素组合中,肺脾气虚证(14.1%)、内闭外脱证(10.6%)、湿热郁肺证(6.0%)、寒湿犯肺证(4.9%)、湿毒犯肺证(4.9%)、热毒犯肺证(4.6%)、气阴两虚证(3.9%)出现频率较高;四证素及其他证素构成的证候单一,无集中性。结论:新冠肺炎的主要病性因素以湿、毒、虚、热、寒、瘀为主,病位主要在肺,累及在脾,常相合为病,或袭于表,或壅于胃肠,或迁延心肝。
Objective:To investigate the distribution and combination of TCM syndromes in adult with COVID-19 based on literature reports.Methods:The literatures on TCM syndromes of COVID-19 were retrieved from CNKI,China biomedical literature database,Wanfang database and VIP database since March 3,2020,and were collected and summarized.SPSS20.0 statistical software was used for statistical description analysis.Results:In 33 syndrome elements,the frequency was listed as following:dampness(82.6%),epidemic toxic(76.8%),deficiency(76.8%),Yang(阳)deficiency(60.9%),fever(59.4%),Yin(阴)deficiency(43.5%),cold(40.6%),and blood stasis(15.9%).Location elements were listed as following:lung(100%),spleen(59.4%),exterior(14.5%),interior(14.5%),stomach(13%),intestinal(10.1%),liver(8.7%),heart(8.7%).In the combination analysis of syndrome elements,the frequency of combinations of 3 elements and 2 elements were the highest(57.7%and 15.8%).In the combination analysis of the 2 syndromes,the epidemic toxin in lung syndrome(7.4%),the lung Qi(气)deficiency syndrome(1.4%),and the lung dampness infection syndrome(1.0%)occurred more frequently.In the combination of 3 syndromes,deficiency of lung Qi(14.1%),internal closure and external collapse in lung(10.6%),dampness and heat in lung(6.0%),cold and wet in lung(4.9%),wet toxin in lung(4.9%),heat and toxin in lung(4.6%),and Qi and Yin deficiency(3.9%)syndromes occurred more frequently.Four syndrome elements and other syndrome elements constituted a single syndrome with no concentration.Conclusion:The main pathogenic factors of COVID-19 were dampness,toxin,deficiency,heat,and cold and blood stasis.The location of lesion in COVID-19 mainly involves the lung,or/and spleen,exterior,gastrointestinal,or liver.
作者
李风雷
黄艳
芦晓帆
张海龙
赵栋梁
LI Fenglei;HUANG Yan;LU Xiaofan;ZHANG Hailong;ZHAO Dongliang
出处
《中医临床研究》
2021年第36期20-22,共3页
Clinical Journal Of Chinese Medicine