摘要
目的探讨食管癌切除术患者预后不良的影响因素。方法回顾性分析2017年7月至2019年8月在我院行食管癌切除术治疗的62例患者的临床资料,统计术后1年内的预后情况,分析预后不良的相关影响因素。结果术后1年内,62例患者中有5例死亡,死亡率为8.06%。单因素分析显示,食管癌切除术患者预后不良可能受吸烟史、TNM分期、手术方式及术后辅助治疗的影响(P<0.05)。Logistic回归分析显示,吸烟史、TNM分期高、手术方式为胸内吻合手术、术后未行辅助治疗是食管癌切除术患者预后不良的危险因素(OR>1,P<0.05)。结论吸烟史、TNM分期高、手术方式为胸内吻合手术、术后未行辅助治疗是食管癌切除术患者预后不良的危险因素,临床可据此进行早期针对性干预,以有效改善患者预后。
Objective To explore the influencing factors of poor prognosis in patients with esophageal cancer resection.Methods The clinical data of 62 patients who were treated with resection of esophageal cancer in our hospital from July 2017 to August 2019 were retrospectively analyzed.The prognosis within 1 year after surgery was counted,and the related influencing factors of poor prognosis were analyzed.Results Within 1 year after surgery,5 of the 62 patients died,with the mortality rate of 8.06%.Univariate analysis showed that the poor prognosis of patients with resection of esophageal cancer may be affected by smoking history,TNM stage,surgical method and postoperative adjuvant therapy(P<0.05).Logistic regression analysis showed that smoking history,high TNM stage,intrathoracic anastomosis surgery and absence of postoperative adjuvant therapy were risk factors for poor prognosis in patients with resection of esophageal cancer(OR>1,P<0.05).Conclusions Smoking history,high TNM stage,intrathoracic anastomosis surgery and absence of postoperative adjuvant therapy are risk factors for poor prognosis in patients with resection of esophageal cancer.Based on this,early targeted intervention can be carried out to effectively improve the prognosis of patients in clinic.
作者
周燕
尚自强
ZHOU Yan;SHANG Ziqiang(Department of Cardiothoracic Surgery,the First Affiliated Hospital of He'nan University of Science and Technology,Luoyang 471000,China;Department of Thoracic Surgery,New District Hospital of the First Affiliated Hospital of He'nan University of Science and Technology,Luoyang 471000,China)
出处
《临床医学工程》
2022年第4期583-584,共2页
Clinical Medicine & Engineering
关键词
食管癌切除术
预后不良
影响因素
Resection of esophageal cancer
Poor prognosis
Influencing factor
