摘要
目的:探讨五味消毒饮加减辅助治疗糖尿病酮症酸中毒(DKA)的临床效果。方法:选取我院2019年1月~2020年4月DKA患者106例,依据不同治疗方案分为观察组(n=53)、对照组(n=53)。两组均给予常规治疗,对照组给予小剂量胰岛素治疗,观察组给予五味消毒饮加减辅助治。比较两组疗效、症状情况、病情相关指标、胰岛素用量、不良反应。结果:观察组总有效率高于对照组(P<0.05);观察组7h、24h内胰岛素用量及平均日用量均低于对照组(P<0.05);观察组尿酮体消失、酸中毒纠正、血糖恢复正常、pH值恢复、平均住院时间均短于对照组(P<0.05);治疗后观察组血糖、Na、肌酐、尿素氮均低于对照组,K、CO_(2)-CP均高于对照组(P<0.05);观察组并发症总发生率与对照组比较无差异(P>0.05)。结论:五味消毒饮加减辅助治疗DKA效果确切,能有效缓解患者症状,减轻胰岛素用量,促进患者健康,且用药安全。
Objective:To investigate the clinical effect of Wuwei Disinfection Drink on diabetic ketoacidosis(DKA).Methods:106 DKA patients in our hospital from January 2019 to April 2020 were selected and divided into observation group(n=53)and control group(n=53),according to different treatment plans.The two groups were given routine treatment,the control group was given small dose of insulin treatment,the observation group was given Wuwei disinfection drink plus or minus auxiliary treatment.Efficacy,symptoms,disease-related indicators,insulin dosage and adverse reactions were compared between the two groups.Results:The total effective rate in observation group was higher than that of control group(P<0.05).The insulin dosage within 7h and 24h and average daily dosage in observation group were lower than those in control group(P<0.05).The urine ketone body disappeared,acidosis corrected,blood glucose returned to normal,pH value recovered and average hospital stay in the observation group were shorter than those in the control group(P<0.05).After treatment,blood glucose,Na,creatinine and urea nitrogen in observation group were lower than those in control group,while K and CO_(2)-CP were higher than those in control group(P<0.05).There was no difference in the total incidence of complications between the observation group and the control group(P>0.05).Conclusion:The addition and subtraction of Wuwei Disinfection Drink is effective in the treatment of DKA,which can effectively relieve the symptoms of patients,reduce the dosage of insulin,promote the health of patients,and safe medication.
作者
梁富庭
侯中宁
Liang Fu-ting;Hou Zhong-ning(Department of Emergency,The People's Hospital of Zhenping,Nanyang 474250,Henan China)
出处
《四川生理科学杂志》
2022年第3期384-386,532,共4页
Sichuan Journal of Physiological Sciences
