期刊文献+

孟鲁司特钠联合福莫特罗干粉吸入剂治疗小儿支气管哮喘的临床疗效观察 被引量:15

下载PDF
导出
摘要 目的探讨在小儿支气管哮喘治疗中应用孟鲁司特钠+福莫特罗干粉吸入剂,对患儿疗效、血清炎性因子、免疫因子水平的影响。方法选取小儿支气管哮喘患儿100例,随机分为对照组和实验组,各50例。对照组采用福莫特罗干粉吸入剂治疗,实验组采用孟鲁司特钠+福莫特罗干粉吸入剂治疗,比较两组疗效差异。结果治疗后,实验组IL-6、CRP水平低于对照组,CD4^(+)、CD8^(+)、CD4^(+)/CD8^(+)水平高于对照组(P<0.05);实验组疗效总优良率高于对照组(P<0.05)。结论在小儿支气管哮喘治疗中,给药孟鲁司特钠联合福莫特罗干粉吸入剂,可有效改善患儿的机体炎症反应,提升免疫水平,整体疗效表现突出。
出处 《贵州医药》 CAS 2022年第4期559-561,共3页 Guizhou Medical Journal
  • 相关文献

参考文献10

二级参考文献112

  • 1中华医学会呼吸病学分会哮喘学组.支气管哮喘防治指南(支气管哮喘的定义、诊断、治疗及教育和管理方案)[J].中华内科杂志,2003,42(11):817-822. 被引量:297
  • 2Nabil N M, Elessawy A F, Hosny K M, et al. The effect of adding long acting beta 2 agonists to inhaled corticosteroids versus increasing dose of inhaled corticosteroids in improving asthma control[J]. Egypt J Chest Dis Tuberc, 2014, 63(4): 761-764.
  • 3Yoshihara S, Kanno N, Fukuda H, et al. Caregiver treatment satisfaction is improved together with children's asthma control: Prospective study for budesonide monotherapy in school-aged children with uncontrolled asthma symptoms [J]. Allergol Intemati, 2015, 64(4): 371-376.
  • 4Hojo M, Iikura M, Hirashima J, et al. A Comparison of Long-Term Anti-Inflammatory Effect of Two ICS/LABA Combination Inhalers; Fix-Dosed Maintenance Therapy with Budesonide/Formoterol and Salmeterol/Fluticasone[J]. Allergol Internati, 2014, 63(1): 103-111.
  • 5Oh Y J, Lee J, Seo J Y, et al. Preparation of budesonide-loaded porous PLGA microparticles and their therapeutic efficacy in a murine asthma model [J]. J Controlled Release, 2011, 50(1): 56-62.
  • 6Kirsten A M, Watz H, Brindicci C, et al. Effects of beclomethason/ formoterol and budesonide/formoterol fixed combinations on lung function and airway inflammation in patients with mild to moderate asthma -An exploratory study[J]. Pulmonary Pharmacol & Therapeuti, 2015, 31(5): 79-84.
  • 7Yagudina R, Kulikov A, Chuchalin A G, et al. PRS47 Optima Model- Based Cost-Utility Analysis of Fixed Combination Salmeterol/ Fluticasone Versus Non-Fixed Combination Budesonide/Formoterol in One Pack for Bronchial Asthma Treatment[J]. Value Health, 2011, 14(7): A496.
  • 8儿童支气管哮喘诊断与防治指南[J].中华儿科杂志,2008,46(10):745-753. 被引量:2515
  • 9沈宁,蔡柏蔷,姚婉贞.支气管舒张剂联合雾化吸入在慢性阻塞性肺疾病中的应用[J].中华结核和呼吸杂志,2008,31(10):766-767. 被引量:54
  • 10舒雪,高蔚.噻托溴铵联合布地奈德治疗轻中度哮喘的临床疗效评价[J].临床肺科杂志,2012,17(3):561-562. 被引量:13

共引文献227

同被引文献183

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部