摘要
目的分析低剂量心脏平扫检查与冠状动脉CT血管造影(CTA)检查在定量心外膜脂肪体积(EATV)的一致程度。方法对临床提示有冠心病征象的208名患者进行低剂量心脏平扫检查及冠状动脉CTA检查,分别在两种检查的图像上测量心外膜脂肪体积,两种检查测量所得心外膜脂肪体积EATV(心脏平扫)和EATV_(CTA)间的相关性采用Pearson相关系数进行评估,采用Bland-Altman分析法评价两者的一致性。将患者分为无斑块组及斑块组,比较两组患者EATV_(心脏平扫)和EATV_(CTA)差异;通过操作者工作特征曲线评估EATV_(心脏平扫)和EATVCTA预测冠状动脉硬化的价值及差异。结果低剂量EATV_(心脏平扫)为103.12±44.01 cm^(3),EATV_(CTA)为106.72±44.14 cm^(3),两者具有显著的相关性(r=0.955,P<0.001);EATV_(心脏平扫)和EATV_(CTA)的一致性均数为-3.5,4.8%(10/208)的点落位于95%CI界限以外(95%CI:24.0930~29.2116,P<0.001);EATV_(心脏平扫)和EATV_(CTA)预测冠状动脉硬化发生的曲线下面积分别为0.601及0.605,差异无统计学意义(P=0.935)。结论低剂量心脏平扫检查与冠状动脉CTA两组检查方法在测量EAT方面具有等效性,对冠状动脉硬化的预测方面两者具有相当的价值。
Objective To study the consistency between low-dose cardiac plain scanning and coronary artery CT angiography(CTA)in quantification of epicardial adipose tissue volume(EATV).Methods A total of 208 patients with clinically suggestive signs of coronary heart disease were examined by low-dose cardiac plain scan and coronary artery CTA.Epicardial fat volume was measured on the images of both examinations respectively.The correlation between epicardial fat volume measured by the two examinations EATV_(cardiac plain scan) and EATV_(CTA) was evaluated by Pearson correlation coefficient.Bland-altman analysis was used to evaluate their consistency.Patients were divided into the plaque free group and the plaque groups,and the differences of EATV_(cardiac plain scan) and EATV_(CTA) between the two groups were compared.ROC curve was used to evaluate the value and difference of EATV_(cardiac plain scan) and EATV_(CTA) in predicting coronary atherosclerosis.Results There was a significant correlation between low-dose EATV cardiac sweep of 103.12±44.01 cm^(3) and EATVCTA of 106.72±44.14 cm^(3)(r=0.955,P<0.001).The mean consistency between EATV_(cardiac plain scan) and EATV_(CTA) was-3.5,with 4.8%(10/208)points falling outside the 95% CI(95% CI:24.0930-29.2116,P<0.001).The area under the curve for predicting by EATV_(cardiac plain scan) and EATV_(CTA) were 0.601 and 0.605 respectively,with no statistical difference between the two groups(P=0.935).Conclusion Low-dose cardiac plain scan and coronary artery CTAare equivalent in the measurement of EAT,and both are of equal value in the prediction of coronary atherosclerosis.
作者
梁健华
林永开
吴洁瑶
邓立维
杨春阳
李远章
LIANG Jianhua;LIN Yongkai;WU Jieyao;DENG Liwei;YANG Chunyang;LI Yuanzhang(Department of Imaging Diagnosis,the Fifth Affiliated Hospital of Southern Medical University,Guangzhou 510999,China)
出处
《分子影像学杂志》
2022年第2期189-193,共5页
Journal of Molecular Imaging
基金
广东省医学科学技术研究基金项目(B2020223)。
