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右美托咪啶在肛肠疾病患者手术麻醉中的效果观察 被引量:1

Efficacy Observation on Dexmedetomidine in Anesthesia for Coloproctological Disease’s Surgery
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摘要 目的:观察右美托咪啶在肛肠疾病患者麻醉中的应用效果。方法:将150例肛肠疾病手术患者随机分为观察组和对照组,每组75例。所有患者均行腰麻-硬膜外联合麻醉,对照组患者使用罗哌卡因进行麻醉,观察组在对照组的基础上持续静脉注射右美托咪啶进行麻醉,对照组患者注射与右美托咪啶等量的生理盐水,观察2组患者神经阻滞情况、运动阻滞情况、生命体征监测、术后镇痛效果及并发症情况。结果:观察组患者神经阻滞起效时间短于对照组(P <0.05),持续时间长于对照组(P <0.05);观察组中运动阻滞评为1分者较对照组少,评为2、3分者多于对照组(P <0.05);麻醉前、麻醉30min后患者生命体征指标组间、组内比较差异无统计学意义(P>0.05);术后观察组患者疼痛评分明显低于对照组(P <0.05);2组患者并发症发生率比较差异无统计学意义(P>0.05)。结论:右美托咪啶用于肛肠疾病患者手术中能够获得更好的麻醉效果,可有效减轻患者术后疼痛,且临床用药安全性较高。 Objective To observe the efficacy of dexmedetomidine(DEX)applied in anesthesia for coloproctological disease’s surgery. Methods The 150 patients with coloproctological diseases all undergoing surgery were randomly divided into control group(75 cases,received associated spinal and epidural anesthesia by using ropiracaine)and observation group(75 cases,based on control groups’ anesthesia,added with long-standing injection of DEX for anesthesia,meanwhile in control group instead of same volume of normal saline).Then,both groups’ patients’ nerve block status,motor block status,monitored vital signs,postoperative analgesia efficacy,and complication status were observed. Results In nerve block onset time observation group was shorter than control group(P <0.05),its long-standing time was longer than control group(P <0.05);in observation group the number of the patients being of motor block ratings=1,and the number of the patients being of the ratings=2,3 were respectively less,and more than that in control group(P <0.05);after surgery observation groups’ patients’ ratings on pain were significantly lower than control group’s patients’ ones(P <0.05)i.nvitalsigns’ norms before anesthesia,and at 30 min after anesthesia there was no statistical difference whether intra-groups or between the two groups(P >0.05);in complication incidence there was no statistical difference between the two groups(P >0.05). Conclusion DEX in anesthesia for coloproctological disease’s surgery can achieve better anesthesia efficacy,and effectively relieve patients’ pain,in which safely is higher.
作者 李乾 LI Qian(Huaibin County’s People’s Hospital,Huaibin,Henan 464400)
出处 《中国肛肠病杂志》 2022年第1期63-65,共3页 Chinese Journal of Coloproctology
关键词 肛肠疾病 手术 右美托咪啶 麻醉 Coloproctological disease Surgery Dexmedetomidine Anesthesia
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