摘要
宫颈癌是我国女性生殖道最常见的恶性肿瘤,严重威胁女性健康。近距离放射治疗可提高肿瘤局部放射剂量,同时减少对正常组织的损伤,是局部晚期宫颈癌治疗中不可或缺的重要组成部分。近年来,三维后装近距离放疗、组织间插植近距离放疗和放射性粒子植入近距离放疗等技术迅猛发展,进一步提高了宫颈癌的治疗效果。三者互为联系,对于偏心肿瘤,腔内后装放射治疗靶区覆盖不全、剂量分布适形度不佳,而组织间插植放射治疗可弥补腔内后装放射治疗的不足。放射性粒子植入放疗具有创伤小、安全性高等特点,为复发性宫颈癌患者提供更多的可能。因此,在临床中应根据患者病情特点,为其制定个体化治疗方案。
Cervical cancer is the most common malignant tumor of female reproductive tract in China,which seriously threatens women′s health.Brachytherapy is an essential component of the treatment of locally advanced cervical cancers.It enables the dose to the tumor to be boosted whilst allowing relative sparing of the normal tissues.In recent years,three-dimensional brachytherapy,interstitial implantation brachytherapy and radioactive seed implantation brachytherapy have developed rapidly.These technologies have improved the treatment effect of cervical cancer and reduced complications.The three factors are interrelated.For eccentric tumor,intracavitary brachytherapy has incomplete target coverage and poor dose distribution conformation,while interstitial implantation brachytherapy can make up for the deficiency of intracavitary brachytherapy.Radioactive seed implantation brachytherapy has the characteristics of low trauma and high safety,providing more possibilities for patients with recurrent cervical cancer.Therefore,individualized treatment plan should be formulated according to the characteristics of the patient′s condition in clinical practice.
作者
金鸽
李魁秀(审校)
郭云峰
高阳阳
JIN Ge;LI Kui-xiu;GUO Yun-feng;GAO Yang-yang(Department of Gynecological Oncology,The Fourth Hospital of Hebei Medical University,Shijiazhuang 050000,China)
出处
《国际妇产科学杂志》
CAS
2022年第2期202-206,共5页
Journal of International Obstetrics and Gynecology
