摘要
通过中医理论体系分析非酒精性脂肪性肝病的病因病机、临床症状及治疗方案,发现临床使用的防治非酒精性脂肪性肝病主要是中医古方(参苓白术散、六味地黄丸、茵陈蒿汤、小柴胡汤、桃核承气汤)、中成药(胆宁片、血脂康胶囊、护肝片、三七脂肝丸)、临床经方验方(苓桂术甘汤、三子养亲汤、养肝解郁颗粒、鹧鸪降脂颗粒)以及常见“药食同源”中药材,其主要通过抗炎、抑制氧化应激等生物机制达到调控肝脏脂质代谢、改善缺氧保护肝细胞完整性从而达到改善NAFLD的效果。
This study mainly analyzed etiology,pathogenesis,clinical symptoms and treatment of nonalcoholic fatty liver disease(NAFLD). It found that some TCM ancient formulas of Shenling Baizhu Powder,Liuwei Dihuang Pill,Yinchenhao Decoction,Xiaochaihu Decoction and Taohe Chengqi Decoction,Chinese patent medicine of Danning Tablet,Xuezhikang Capsule,Hugan Tablet,Sanqi Zhigan Pill,as well as clinical empirical formulas of Linggui Zhugan Decoction,Sanzi Yangqin Decoction,Yanggan Jieyu Granule and Zhegu Jiangzhi Granule are mainly applied to prevent and treat NAFLD. The mechanisms are related to anti-inflammation and inhibition of oxidative stress by regulating lipid metabolism of liver and improving anoxia and protecting integrity of liver cells,thus to enhance the curative effect of NAFLD.
作者
王雅丽
张慧翔
李文林
杨丽丽
曾莉
WANG Yali;ZHANG Huixiang;LI Wenlin;YANG Lili;ZENG Li(Nanjing University of Chinese Medicine,Nanjing 210023,China)
出处
《中医药信息》
2022年第4期85-89,共5页
Information on Traditional Chinese Medicine
基金
国家自然科学基金项目(81673982,81704084)
国家重点研发计划项目(2017YFC1703506)
药食同源食材健康功效数据库建设项目(2019007)
研究生创新科研计划项目(KYCX21_1667)。
