摘要
目的:探讨高压氧配合早期综合康复护理对缺氧缺血性脑病早产儿行为智能发育及后遗症影响。方法:选择2018年4月至2020年4月收治的缺氧缺血性脑病(HIE)早产儿100例,随机分为对照组(n=33)、研究A组(n=33)、研究B组(n=34)。对照组患儿接受常规对症支持治疗,在对照组基础上研究A组同时进行高压氧治疗,研究B组患儿同时进行高压氧治疗与早期综合康复护理干预,评估并比较3组患儿行为智能发育情况及神经系统后遗症发生情况。结果:研究A组、B组患儿14日龄、28日龄神经行为发育评估(NBNA)得分均高于对照组,3月龄、6月龄心理运动发育指数(PDI)与智力发育指数(MDI)均高于对照组,12月龄时社交、语言、大动作、精细动作等能区的发育商(DQ)评分均高于对照组,且后遗症发生率低于对照组,差异有统计学意义(P<0.05)。研究B组患儿14日龄、28日龄NBNA得分均高于研究A组,3月龄、6月龄PDI指数与MDI指数均高于研究A组,12月龄时社交、语言、大动作、精细动作等能区DQ评分均高于研究A组,差异有统计学意义(P<0.05)。结论:高压氧配合早期综合康复护理可改善缺血性脑病早产儿神经系统功能,促进神经行为发育与智能发育,降低后遗症发生率。
Objective:To analyze the effects of hyperbaric oxygen combined with early comprehensive rehabilitation measures on promoting behavior and intelligence development in preterm infants with hypoxic-ischemic encephalopathy and the effects on sequela.Methods:A total of 100 cases of HIE premature infants admitted in the hospital from April 2018 to April 2020 were included and were randomly divided into control group(n=33),intervention group A(n=33)and intervention group B(n=34).Children in the control group received routine symptomatic supportive treatment.Intervention group A received hyperbaric oxygen therapy based on control group,and intervention group B received hyperbaric oxygen therapy combined with early comprehensive rehabilitation based on control group.Behavior and intelligence development and the occurrence of neurological sequelae were evaluated and compared between different groups.Results:The NBNA scores of the 14-day and 28-day after birth in intervention group A and B were significantly higher than those of the control group,and the PDI index and MDI index were significantly higher than those of the control group at 6 and 12 months after birth.The DQ scores of language,motor and fine motor areas were significantly higher than those of the control group and the incidence of sequela was significantly lower than those of the control group at 12 months after birth(P<0.05).The NBNA scores of the 14-day and 28-day after birth in intervention group B were higher than those in intervention group A,and the PDI index and MDI index were higher than those in intervention group A at 3 months and 6 months after birth.The DQ scores of language,motor and fine motor areas in intervention group B were significantly higher than those of the intervention group A(P<0.05).Conclusion:Hyperbaric oxygen combined with early comprehensive rehabilitation measures can improve neurological function and promote neurobehavioral development and intelligent development,meanwhile,reduce the incidence of sequela in preterm infants with ischemic encephalopathy.
作者
王晶
张晓玲
董悦
WANG Jing;ZHANG Xiaoling;DONG Yue(The People’s Hospital of Jianhu,Jiangsu Province,Jiangsu Yancheng 224700;The Second People’s Hospital of Jianhu,Jiangsu Province)
出处
《天津护理》
2022年第2期169-173,共5页
Tianjin Journal of Nursing
关键词
高压氧
康复护理
缺氧缺血性脑病
早产儿
神经行为发育
智能发育
后遗症
Hyperbaric oxygen
Early comprehensive rehabilitation
Hypoxic ischemic encephalopathy
Premature infant
Neurobehavioral development
Intelligent development
Sequela
