摘要
目的分析某医院肝胆外科住院患者抗菌药物临床应用情况。方法选择2020年1月至2021年8月乌兰察布市中心医院肝胆外科住院患者2799例的临床资料进行回顾性分析。比较2020年1~12月与2021年1~8月每月平均抗生素药物使用强度、使用率,人均DDD/d实际值。统计2020年1月至2021年8月不合理应用抗生素情况。结果2020年1~12月平均抗菌药物使用强度(84.03±3.59),2021年1~8月抗菌药物使用强度(86.22±4.50),差异无统计学意义(P>0.05);2020年1~12月平均使用率(77.27±11.07)%,2021年1~8月(78.26±13.19)%,差异无统计学意义(P>0.05);2020年1~12月平均人均DDD/d实际值0.92±0.12,2021年1~8月为(0.91±0.14),差异无统计学意义(P>0.05)。2020年1~12月不合理应用抗菌药物23例(占1.56%),2021年1~8月为7例(50.75%),2020年1—12月不合理应用抗菌药物比例显著高于2021年1~8月,差异有统计学意义(P<0.05)。2020年1~12月不合理应用抗菌药物中药物选用不合理比例显著高于2021年1~8月,差异有统计学意义(P<0.05)。结论肝胆外科住院患者抗菌药物应用率较高。用药强度普遍较高;2021年不合理应用抗菌药物比例较2020年显著下降。不合理应用抗菌药物中药物选用不合理的比例相对较好,临床工作中还需要规范抗生素的应用。
Objective To analyze the clinical application of antibiotics in inpatients of Department of Hepatobiliary Surgery in a hospital.Methods The clinical data of 2799 inpatients of Department of Hepatobiliary Surgery in our hospital from January 2020 to August 2021 were selected and retrospectively analyzed.The actual values of monthly average antibiotic drug use intensities,utilization rates and per capita DDD/day were compared between from January 2020 to December 2020 and from January 2021 to August 2021.Statistics on irrational use of antibiotics from January 2020 to August 2021 were made.Results The average intensity of antibiotics use from January to December in 2020 was(84.03±3.59),and that from January to August in 2021 was(86.22±4.50),with no statistically significant difference(P>0.05).The average utilization rates were(77.27±11.07%)from January to December in 2020 and(78.26±13.19)%from January to August in 2021,with no statistically significant difference(P>0.05).The actual average per capita DDD/day from January to December in 2020 was(0.92±0.12),and that from January to August in 2021 was(0.91±0.14),with no statistically significant difference(P>0.05).A total of 23 patients(1.56%)had irrational use of antibiotics from January to December in 2020,and 7 patients(0.75%)had that from January to August in 2021.The proportion of irrational use of antibiotics from January to December in 2020 was significantly higher than that from January to August in 2021,with statistically significant difference(P<0.05).The proportion of irrational use of antibiotics in the period from January to December in 2020 was significantly higher than that in the period from January to August in 2021,with statistically significant difference(P<0.05).Conclusion The application rate of antibiotics is higher in inpatients in the Department of Hepatobiliary Surgery.The drug intensity is generally higher.The proportion of irrational use of antibiotics in 2021 was significantly lower than that in 2020.In the irrational use of antibiotics,the proportion of irrational drug selection is relatively high,and the application of antibiotics should be standardized in clinical work.
作者
牛角
NIU Jiao(Department of Pharmacy,Ulanqab Central Hospital,Ulanqab012000,China)
出处
《中国现代医生》
2022年第7期109-111,115,共4页
China Modern Doctor
关键词
肝胆外科
住院患者
抗菌药物
应用分析
Department of hepatobiliary surgery
Inpatient
Antibiotics
Application analysis
