摘要
Gallbladder carcinoma(GBC)is a highly malignant tumor of the digestive system,and the 5-year survival rate of stage IVb is only 2%(1).For unresectable GBC,although the guidelines published by the National Comprehensive Cancer Network(NCCN)in 2019 recommended radiotherapy combined with chemotherapy as the first-line treatment,no promising prognosis has been reported(2).Conversion therapy refers to the achievement of long-term survival by radical surgery in some patients with advanced cancer on the premise that systemic therapy will be effective(3,4).Herein,we reported the case of a 61-year-old male patient with stage IVb GBC who was diagnosed with multiple abdominal,retroperitoneal,mediastinal,and bilateral hilar lymph nodes.The results of follow-up showed that the patient achieved a disease-free survival(DFS)of 11.3 months and overall survival(OS)of 18.1 months after conversion therapy.